Cleveland Browns quarterback Brian Hoyer left the game with a right knee injury Thursday night against the Buffalo Bills and his return is questionable.

Hoyer was replaced by Brandon Weeden, who missed the past two games with a sprained thumb.

Hoyer got injured when he was sliding and was hit by Bills rookie middle linebacker Kiko Alonso.

Hoyer had played exceptionally well, winning two games as a starter since taking over for Weeden.

The hometown product is now sidelined in all likelihood for the remainder of this game.

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Aaron Wilson covers the Ravens for The Baltimore Sun.