TENNESSEE TITANS at HOUSTON TEXANS

START: Chris Johnson, Bo Scaife (deeper leagues), Rob Bironas, Matt Schaub, Arian Foster, Andre Johnson, Neil Rackers, Houston D/ST (deeper leagues)

SIT: Rusty Smith, Kerry Collins, Javon Ringer, Randy Moss, Nate Washington, Justin Gage, Tennessee D/ST, Derrick Ward, Kevin Walter, Jacoby Jones, Joel Dreessen, Owen Daniels

JACKSONVILLE JAGUARS at NEW YORK GIANTS

START: Maurice Jones-Drew (game-time decision), Marcedes Lewis

SIT: David Garrard, Rashad Jennings, Mike Sims-Walker, Mike Thomas, Jacksonville D/ST, Josh Scobee

CAROLINA PANTHERS at CLEVELAND BROWNS

START: Peyton Hillis, Cleveland D/ST

SIT: Colt McCoy, Jake Delhomme, Mike Bell, Mohammed Massaquoi, Brian Robiskie, Ben Watson, Phil Dawson

PITTSBURGH STEELERS at BUFFALO BILLS

START: Ben Roethlisberger, Rashard Mendenhall, Hines Ward, Mike Wallace, Heath Miller, Pittsburgh D/ST, Shaun Suisham, Stevie Johnson (WR2/3)

SIT: Ryan Fitzpatrick, Fred Jackson, C.J. Spiller, Lee Evans, Shawn Nelson, Buffalo D/ST, Rian Lindell

KANSAS CITY CHIEFS at SEATTLE SEAHAWKS

START: Matt Cassel, Jamaal Charles, Thomas Jones (flex, deeper leagues), Dwayne Bowe, Ryan Succop

SIT: Chris Chambers, Tony Moeaki, Kansas City D/ST

MIAMI DOLPHINS at OAKLAND RAIDERS

START: Ronnie Brown, Davone Bess (WR3, deeper leagues), Brian Hartline (WR3, deeper leagues), Dan Carpenter (deeper leagues), Miami D/ST (deeper leagues), Darren McFadden, Zach Miller, Oakland D/ST, Sebastian Janikowski

SIT: Chad Henne, Tyler Thigpen, Ricky Williams, Brandon Marshall (injured), Anthony Fasano, Jason Campbell, Bruce Gradkowski, Michael Bush, Jacoby Ford, Darrius Heyward-Bey, Johnny Lee Higgins

ST. LOUIS RAMS at DENVER BRONCOS

START: Kyle Orton, Knowshon Moreno, Brandon Lloyd, Matt Prater

SIT: Correll Buckhalter, Laurence Maroney, Jabar Gaffney, Eddie Royal, Daniel Graham, Denver D/ST

TAMPA BAY BUCCANEERS at BALTIMORE RAVENS

START: Joe Flacco (deeper leagues), Ray Rice, Anquan Boldin, Todd Heap, Baltimore D/ST, Billy Cundiff

SIT: Willis McGahee, Le’Ron McClain, Derrick Mason, T.J. Houshmandzadeh

SAN DIEGO CHARGERS at INDIANAPOLIS COLTS

START: Philip Rivers, Mike Tolbert, Vincent Jackson, Antonio Gates (if activated), Nate Kaeding, Peyton Manning, Reggie Wayne (WR2), Pierre Garcon (WR3, deeper leagues), Jacob Tamme, Adam Vinatieri

SIT: Ryan Mathews (injured), Darren Sproles, Malcom Floyd, Legedu Naanee, Patrick Crayton, Randy McMichael, San Diego D/ST, Donald Brown, Joseph Addai, Mike Hart, Austin Collie, Blair White, Indianapolis D/ST