Pittsburgh Steelers defensive end Brett Keisel is likely out for the season with a left triceps injury.
"You don't want to see anyone get hurt, especially someone like that where he won't be back for the rest of the season," outside linebacker James Harrison said.
Keisel has played well since returning, with a sack and an interception.
"I'm really disappointed," veteran strong safety Troy Polamalu said.
"It almost makes you want to cry when you lose a player like that because he's so instrumental to who we are and what we try to do here," safety Mike Mitchell said. "Everyone's got to pick it up."
Ben Roethlisberger injured his hand, throwing a pair of interceptions.
Follow me on Twitter: @RavensInsider
Aaron Wilson covers the Ravens for The Baltimore Sun