Dec 12, 2020; Columbia, Missouri, USA; A detailed view of a Georgia Bulldogs helmet during the second half against the Missouri Tigers at Faurot Field at Memorial Stadium. Mandatory Credit: Jay Biggerstaff-USA TODAY Sports

College football Week 10 picks

Week 10 of the college football betting season kicks off with a trio of best bets, including a call on the Battle of Oklahoma.

Check out the Oklahoma State vs Oklahoma pick, as well as SEC action in Georgia vs Missouri and Pac 12 predictions as USC battles Washington.

Get the latest lines, great same-game parlay specials and cool customer offers at Draft Kings Sportsbook.

Missouri at Georgia (-15.5)

Georgia posted a win for bettors last week in their 43-20 win over Florida as 14-point favorites but they’re still only 2-5-1 against the spread this season, and 1-4-1 ATS in their last six. At home the Bulldogs have won 22 straight but they’re 8-13-1 ATS.

Missouri has been a solid bet lately at 5-1 ATS in their last six. As an underdog the Tigers are 7-2 ATS in their last nine. They’re 6-3 ATS in their last nine versus the Bulldogs which includes a four-game ATS winning streak in Georgia.

Pick: Missouri +15.5

Washington at USC (+3.5)

Washington may be perfect on the season at 8-0, but it hasn’t translated to winnings for bettors with a 3-4-1 ATS record. That includes going 0-3-1 ATS in their last four. When favored they’ve won 13 straight with a 5-7-1 ATS record.

USC let down bettors again last week in their 50-49 loss to California as 10-point favorites. To put in bluntly the Trojans’ defense stinks. USC has lost six straight ATS and they’re 2-7 ATS on the season. Even though Washington’s ATS results have been poor lately, USC’s have been even worse. We’ll go with the Huskies here.

Pick: Washington -3.5

Oklahoma at Oklahoma State (+6)

Oklahoma is coming off their first loss of the season after falling to Kansas 38-33 as 7.5-point favorites last week. The Sooners have now dropped their last two games ATS. On the road they’re a mediocre 2-3 SU and ATS in their last five and they haven’t been much better as a road favorite at 5-5 SU and 4-6 ATS in their last 10

Oklahoma State has been a good bet recently with four straight wins ATS. As an underdog they’ve won three straight both SU and ATS, and as a home underdog they’ve won their last four games. In their last 10 games as a home underdog the Cowboys are a profitable 8-2 SU and ATS.

Pick: Oklahoma State (+6)

Upcoming Games

Oct 9th, 7:30 PM

New Mexico State +14.5 -115

Jacksonville State -14.5 -115

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Oct 10th, 7:30 PM

Coastal Carolina +11.5 -115

James Madison -11.5 -115

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Oct 10th, 8:00 PM

Middle Tennessee +4.5 -115

LA Tech -4.5 -115

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Oct 10th, 8:00 PM

UTEP +20.5 -122

WKU -20.5 -122

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Oct 11th, 8:00 PM

Northwestern +10.5 -115

Maryland -10.5 -115

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Oct 11th, 9:00 PM

UNLV -17.5 -115

Utah State +17.5 -115

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Oct 11th, 10:30 PM

Utah (16) -5.5 -122

Arizona State +5.5 -122

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Oct 12th, 12:00 PM

UAB +23.5 -115

Army -23.5 -115

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Oct 12th, 12:00 PM

South Carolina +21.5 -110

Alabama (7) -21.5 -110

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Oct 12th, 12:00 PM

Missouri (21) -27.5 -115

Massachusetts +27.5 -115

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Oct 12th, 12:00 PM

Ball State -6.5 -115

Kent State +6.5 -115

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Oct 12th, 12:00 PM

Toledo -8.5 -115

Buffalo +8.5 -115

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Oct 12th, 12:00 PM

Clemson (10) -18.5 -118

Wake Forest +18.5 -118

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Oct 12th, 12:00 PM

Georgia Tech -4.5 -110

North Carolina +4.5 -110

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Oct 12th, 12:00 PM

Washington +4.5 -110

Iowa -4.5 -110

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Oct 12th, 12:00 PM

Wisconsin +2.5 -115

Rutgers -2.5 -115

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Oct 12th, 2:00 PM

Miami-OH -3.5 -115

Eastern Michigan +3.5 -115

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Oct 12th, 3:30 PM

Memphis -4.5 -115

USF +4.5 -115

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Oct 12th, 3:30 PM

San Jose State -2.5 -115

Colorado State +2.5 -115

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Oct 12th, 3:30 PM

San Diego State -1.5 -122

Wyoming +1.5 -122

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Oct 12th, 3:30 PM

Texas (1) -10.5 -115

Oklahoma (18) +10.5 -115

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Oct 12th, 3:30 PM

Old Dominion +1.5 -115

Georgia State -1.5 -115

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Oct 12th, 3:30 PM

Cincinnati +6.5 -115

UCF -6.5 -115

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Oct 12th, 3:30 PM

Akron +9.5 -110

Western Michigan -9.5 -110

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Oct 12th, 3:30 PM

NIU +2.5 -115

Bowling Green -2.5 -115

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Oct 12th, 3:30 PM

California +2.5 -115

Pittsburgh (22) -2.5 -115

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Oct 12th, 3:30 PM

Louisville -7.5 -120

Virginia +7.5 -120

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Oct 12th, 3:30 PM

Stanford +21.5 -115

Notre Dame (11) -21.5 -115

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Oct 12th, 3:30 PM

Purdue +17.5 -115

Illinois (23) -17.5 -115

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Oct 12th, 3:30 PM

Penn State (4) -4.5 -115

USC +4.5 -115

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Oct 12th, 4:00 PM

Arizona -2.5 -115

BYU (14) +2.5 -115

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Oct 12th, 4:00 PM

Ohio -1.5 -110

Central Michigan +1.5 -110

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Oct 12th, 4:15 PM

Mississippi State +34.5 -122

Georgia (5) -34.5 -122

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Oct 12th, 5:00 PM

Southern Miss +6 -110

Louisiana-Monroe -6 -110

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Oct 12th, 7:00 PM

North Texas -7 -105

Florida Atlantic +7 -105

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Oct 12th, 7:00 PM

UTSA -4 -110

Rice +4 -110

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Oct 12th, 7:00 PM

Air Force +3.5 -115

New Mexico -3.5 -115

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Oct 12th, 7:00 PM

Washington State -2.5 -104

Fresno State +2.5 -104

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Oct 12th, 7:00 PM

Florida +10.5 -115

Tennessee (8) -10.5 -115

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Oct 12th, 7:00 PM

Arkansas State +13.5 -122

Texas State -13.5 -122

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Oct 12th, 7:30 PM

Oregon State -4.5 -115

Nevada +4.5 -115

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Oct 12th, 7:30 PM

Ole Miss (9) +2.5 -110

LSU (13) -2.5 -110

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Oct 12th, 7:30 PM

Appalachian State +10 -116

Louisiana-Lafayette -10 -116

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Oct 12th, 7:30 PM

Ohio State (2) +1.5 -115

Oregon (3) -1.5 -115

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Oct 12th, 7:45 PM

Vanderbilt +11.5 -115

Kentucky -11.5 -115

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Oct 12th, 8:00 PM

Marshall -2.5 -115

Georgia Southern +2.5 -115

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Oct 12th, 8:00 PM

Iowa State (11) -2.5 -110

West Virginia +2.5 -110

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Oct 12th, 8:00 PM

Syracuse -2.5 -115

NC State +2.5 -115

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Oct 12th, 9:00 PM

Minnesota -6.5 -115

UCLA +6.5 -115

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Oct 12th, 10:15 PM

Kansas State (18) -6 -110

Colorado +6 -110

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Oct 12th, 11:00 PM

Boise State (17) -20.5 -115

Hawaii +20.5 -115

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Oct 15th, 7:30 PM

Troy

South Alabama

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Oct 15th, 8:00 PM

Kennesaw State

Middle Tennessee

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Oct 15th, 9:00 PM

LA Tech

New Mexico State

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Oct 16th, 7:00 PM

WKU

Sam Houston State

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Oct 16th, 9:00 PM

Florida International (FIU)

UTEP

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