Looking for reasons to fade the San Francisco 49ers as 7-point underdogs at Buffalo on Sunday Night?
Injuries? Check. Cross-country travel? Check. Bills healthy and off a bye week? Check.
Let’s throw in wintry snowy weather for the team from California? Check.
Buffalo is 14-1 SU as favorites and 19-4 SU vs the NFC and can win in a blowout here.
49ers Bills Pick: Odds BUF -7 Total, 44.5 | Matchup Report
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Check Brock Purdy’s status here because, without him, these reasons evaporate. San Francisco has injuries galore and are probably not a playoff team.
But the pressure is on the Bills and the weather can wreak havoc on both teams to keep this game within a TD.
Buffalo has been on a roll, comes off a win over KC and with two weeks to healthy for depleted 49ers team. They usually win as favorites, they always win non-conference games and Josh Allen wants to polish his MVP credential.
All the trends lean Buffalo and the situational factors also call for fading the 49ers even as a TD dog.
The weather might keep this game a low-scoring affair but it will also keep the 49ers from scoring much at all. This feels like 21-7 for Bills.
Bills are 14-1 SU in their last 15 games when favored
49ers are 2-10 ATS in their last 12 Sunday games.
49ers are 1-5 ATS in their last 6 games on the road.
49ers failed to cover five straight Sunday road games
Bills have played 8 straight home OVERs
Bills are 19-4 SU in their last 23 non-conference games
Bills won 10 straight December games SU
OVER is 11-2 Buffalo’s last 13 games as faves.