Oct 24, 2020; Clemson, South Carolina, USA;   Clemson quarterback Trevor Lawrence (16) waves to fans after their game against Syracuse at Memorial Stadium. Mandatory Credit: Ken Ruinard-USA TODAY Sports

Clemson vs Notre Dame: opening lines report

Week 10 in college football features two interesting ranked matchups, including to Top 10 teams squaring off and a Top 5 matchup that could have future playoff implications.

The Top 5 matchup pits the No. 1 Clemson Tigers against the No. 4 Notre Dame Fighting Irish. When the lines were first posted the Tigers were listed as a 7.5-point road favorite, but that was quickly bet down to -5.5 by Monday.

Last week, without starting quarterback Trevor Lawrence, sidelined by COVID-19, the Tigers escaped with a 34-28 win over the Boston College Eagles as a 26.5-point favorite. The Fighting Iris have won their last three games as a home underdog. [ Matchup Report and Game Props

College Football opening lines

In the other notable ranked matchup the No. 8 Florida Gators take on the No. 5 Georgia Bulldogs. The opening odds for this game peg the Bulldogs as a 2.5-point favorite. Georgia has won their last three games against Florida both straight up and against the spread. [ Matchup Report and live odds

The largest spread on the early odds list this week belongs to the Marshall Thundering Herd. They’re a 43.5-point home favorite versus the Massachusetts Minutemen. Marshall heads into this game having won five straight at 4-1 ATS.

Two other games on the schedule this week also boast spreads of 20 points or high. First up, the Oklahoma Sooners opened as a 37-point home favorite against the Kansas Jayhawks. In their last 22 games when favored by 37 points or more the Sooners are 22-0 SU and 14-7-1 ATS.

In the Big Ten the Penn State Nittany Lions opened as a 24.5-point home favorite versus the Maryland Terrapins. Penn state has gotten off to a lousy start this season, losing their first two games SU. They’re also 2-5 ATS in their last seven.

The early odds included 16 road teams listed as the favorite this week. The largest road favorite when the lines opener were the Appalachian State Mountaineers. They opened as a 17-point road favorite against the Texas State Bobcats. The Mountaineers have faced large spread in almost every game this season, and they’ve disappointed bettors with a 1-4 ATS record.

Also noteworthy for bettors this week is the return of the Pac-12. They kickoff their season this weekend and a few opening lines included Washington at California (+3.5), and Washington State at Oregon State (-3).

Get live college football odds updated for every game as well as statistical breakdowns for every game.

Upcoming Games

Nov 28th, 7:00 PM

LSU +15.5 -110

Texas A&M (5) -15.5 -110

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Nov 28th, 7:00 PM

Kansas State +5.5 -110

Baylor -5.5 -110

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Nov 28th, 7:00 PM

Duke -2.5 -110

Georgia Tech +2.5 -110

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Nov 28th, 7:30 PM

Georgia (13) -22 -110

South Carolina +22 -110

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Nov 28th, 7:30 PM

Utah +9 -110

Washington -9 -110

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Nov 28th, 8:00 PM

Arizona +7.5 -110

UCLA -7.5 -110

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Nov 28th, 8:00 PM

TCU -23 -110

Kansas +23 -110

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Nov 28th, 11:00 PM

Nevada -7 -110

Hawaii +7 -110

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Dec 1st, 10:30 AM

WKU +1.5 -110

Charlotte -1.5 -110

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Dec 3rd, 9:30 PM

Air Force

Utah State

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Dec 4th, 7:00 PM

Louisiana-Lafayette (23)

Appalachian State

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Dec 4th, 9:00 PM

Washington State

USC (19)

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Dec 4th, 9:30 PM

Boise State

UNLV

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Dec 5th, 12:00 PM

Ohio State (3)

Michigan State

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Dec 5th, 12:00 PM

Memphis

Tulane

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Dec 5th, 12:00 PM

Kent State

Miami-OH

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Dec 5th, 12:00 PM

Toledo

NIU

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Dec 5th, 12:00 PM

Cincinnati (7) -3.5 -110

Tulsa (24) +3.5 -110

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Dec 5th, 2:00 PM

Eastern Michigan

Western Michigan

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Dec 5th, 2:00 PM

Bowling Green

Akron

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Dec 5th, 2:00 PM

Troy -5.5 -110

South Alabama +5.5 -110

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Dec 5th, 2:30 PM

Syracuse

Notre Dame (2)

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Dec 5th, 2:33 PM

Florida (6) -6.5 -110

Tennessee +6.5 -110

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Dec 5th, 2:33 PM

Vanderbilt

Georgia (13)

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Dec 5th, 2:33 PM

Texas A&M (5) +3 -110

Auburn (22) -3 -110

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Dec 5th, 2:33 PM

South Carolina

Kentucky

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Dec 5th, 2:33 PM

Colorado

Arizona

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Dec 5th, 2:33 PM

UCLA

Arizona State

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Dec 5th, 2:33 PM

Oregon (9)

California

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Dec 5th, 2:33 PM

Stanford

Washington

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Dec 5th, 2:33 PM

Baylor +14 -110

Oklahoma (14) -14 -110

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Dec 5th, 2:33 PM

Texas (20)

Kansas State

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Dec 5th, 2:33 PM

Oklahoma State (21) +1 -110

TCU -1 -110

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Dec 5th, 2:33 PM

Kansas

Texas Tech

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Dec 5th, 2:33 PM

West Virginia

Iowa State (15)

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Dec 5th, 2:33 PM

Northwestern (11)

Minnesota

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Dec 5th, 2:33 PM

Nebraska

Purdue

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Dec 5th, 2:33 PM

Iowa

Illinois

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Dec 5th, 2:33 PM

Penn State

Rutgers

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Dec 5th, 2:33 PM

Ball State

Central Michigan

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Dec 5th, 2:33 PM

Fresno State

Nevada

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Dec 5th, 2:33 PM

Boston College

Virginia

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Dec 5th, 2:33 PM

Clemson (4)

Virginia Tech

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Dec 5th, 2:33 PM

Florida State

Duke

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Dec 5th, 2:33 PM

Georgia Tech

NC State

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Dec 5th, 2:33 PM

Liberty

Coastal Carolina (16)

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Dec 5th, 2:33 PM

Western Carolina

North Carolina (25)

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Dec 5th, 2:33 PM

Oregon State

Utah

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Dec 5th, 2:33 PM

Arkansas

Missouri

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Dec 5th, 3:00 PM

Louisiana-Monroe +20 -110

Arkansas State -20 -110

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Dec 5th, 3:30 PM

Indiana (12) +15.5 -110

Wisconsin (18) -15.5 -110

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Dec 5th, 3:30 PM

Maryland

Michigan

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Dec 5th, 3:30 PM

Buffalo

Ohio

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Dec 5th, 4:00 PM

Hawaii

San Jose State

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Dec 5th, 6:00 PM

Florida Atlantic +3 -105

Georgia Southern -3 -105

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Dec 5th, 7:00 PM

Colorado State

San Diego State

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Dec 5th, 10:30 PM

Wyoming

New Mexico

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