Oct 24, 2020; Clemson, South Carolina, USA;   Clemson quarterback Trevor Lawrence (16) waves to fans after their game against Syracuse at Memorial Stadium. Mandatory Credit: Ken Ruinard-USA TODAY Sports

Clemson vs Notre Dame: opening lines report

Week 10 in college football features two interesting ranked matchups, including to Top 10 teams squaring off and a Top 5 matchup that could have future playoff implications.

The Top 5 matchup pits the No. 1 Clemson Tigers against the No. 4 Notre Dame Fighting Irish. When the lines were first posted the Tigers were listed as a 7.5-point road favorite, but that was quickly bet down to -5.5 by Monday.

Last week, without starting quarterback Trevor Lawrence, sidelined by COVID-19, the Tigers escaped with a 34-28 win over the Boston College Eagles as a 26.5-point favorite. The Fighting Iris have won their last three games as a home underdog. [ Matchup Report and Game Props

College Football opening lines

In the other notable ranked matchup the No. 8 Florida Gators take on the No. 5 Georgia Bulldogs. The opening odds for this game peg the Bulldogs as a 2.5-point favorite. Georgia has won their last three games against Florida both straight up and against the spread. [ Matchup Report and live odds

The largest spread on the early odds list this week belongs to the Marshall Thundering Herd. They’re a 43.5-point home favorite versus the Massachusetts Minutemen. Marshall heads into this game having won five straight at 4-1 ATS.

Two other games on the schedule this week also boast spreads of 20 points or high. First up, the Oklahoma Sooners opened as a 37-point home favorite against the Kansas Jayhawks. In their last 22 games when favored by 37 points or more the Sooners are 22-0 SU and 14-7-1 ATS.

In the Big Ten the Penn State Nittany Lions opened as a 24.5-point home favorite versus the Maryland Terrapins. Penn state has gotten off to a lousy start this season, losing their first two games SU. They’re also 2-5 ATS in their last seven.

The early odds included 16 road teams listed as the favorite this week. The largest road favorite when the lines opener were the Appalachian State Mountaineers. They opened as a 17-point road favorite against the Texas State Bobcats. The Mountaineers have faced large spread in almost every game this season, and they’ve disappointed bettors with a 1-4 ATS record.

Also noteworthy for bettors this week is the return of the Pac-12. They kickoff their season this weekend and a few opening lines included Washington at California (+3.5), and Washington State at Oregon State (-3).

Get live college football odds updated for every game as well as statistical breakdowns for every game.

Upcoming Games

Aug 27th, 12:00 PM

Austin Peay

WKU

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Aug 27th, 12:30 PM

Nebraska -10.5 -107

Northwestern +10.5 -107

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Aug 27th, 3:30 PM

Idaho State

UNLV

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Aug 27th, 3:33 PM

Nevada -16.5 -110

New Mexico State +16.5 -110

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Aug 27th, 4:00 PM

Wyoming +8.5 -110

Illinois -8.5 -110

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Aug 27th, 4:00 PM

UCONN +29.5 -110

Utah State -29.5 -110

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Aug 27th, 5:00 PM

Duquesne

Florida State

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Aug 27th, 7:00 PM

Charlotte +5.5 -110

Florida Atlantic -5.5 -110

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Aug 27th, 8:15 PM

Florida A&M

North Carolina

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Aug 27th, 9:00 PM

North Texas -4 -110

UTEP +4 -110

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Aug 27th, 10:30 PM

Vanderbilt -4.5 -110

Hawaii +4.5 -110

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Sep 1st, 6:00 PM

St. Francis-PA

Akron

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Sep 1st, 7:00 PM

Ball State +27.5 -110

Tennessee -27.5 -110

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Sep 1st, 7:00 PM

Central Michigan +19 -110

Oklahoma State (12) -19 -110

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Sep 1st, 7:00 PM

West Virginia +7.5 -107

Pittsburgh (17) -7.5 -107

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Sep 1st, 7:00 PM

South Carolina State

UCF

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Sep 1st, 7:00 PM

Bryant

Florida International (FIU)

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Sep 1st, 7:00 PM

LIU

Toledo

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Sep 1st, 7:30 PM

VMI

Wake Forest (22)

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Sep 1st, 8:00 PM

LA Tech +16 -107

Missouri -16 -107

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Sep 1st, 8:00 PM

Penn State -3.5 -107

Purdue +3.5 -107

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Sep 1st, 8:00 PM

Eastern Illinois

NIU

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Sep 1st, 8:00 PM

Alabama A&M

UAB

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Sep 1st, 9:00 PM

New Mexico State +37.5 -107

Minnesota -37.5 -107

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Sep 1st, 10:00 PM

Northern Arizona

Arizona State

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Sep 1st, 10:30 PM

Cal Poly

Fresno State

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Sep 1st, 10:30 PM

Portland State

San Jose State

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Sep 2nd, 7:00 PM

Virginia Tech -7.5 -107

Old Dominion +7.5 -107

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Sep 2nd, 7:00 PM

Western Michigan +20 -107

Michigan State (15) -20 -107

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Sep 2nd, 7:00 PM

Eastern Kentucky

Eastern Michigan

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Sep 2nd, 7:00 PM

William & Mary

Charlotte

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Sep 2nd, 7:30 PM

Temple +6.5 -110

Duke -6.5 -110

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Sep 2nd, 8:00 PM

Tennessee Tech

Kansas

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Sep 2nd, 8:00 PM

Illinois +3.5 +103

Indiana -3.5 +103

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Sep 2nd, 10:00 PM

TCU -9 -107

Colorado +9 -107

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Sep 3rd, 12:00 PM

Sam Houston State

Texas A&M (6)

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Sep 3rd, 12:00 PM

Rutgers +9 -110

Boston College -9 -110

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Sep 3rd, 12:00 PM

NC State (13) -10 -110

East Carolina +10 -110

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Sep 3rd, 12:00 PM

North Carolina -4 -110

Appalachian State +4 -110

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Sep 3rd, 12:00 PM

South Dakota State

Iowa

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Sep 3rd, 12:00 PM

Buffalo +20.5 -110

Maryland -20.5 -110

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Sep 3rd, 12:00 PM

Colorado State +30 -110

Michigan (8) -30 -110

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Sep 3rd, 12:00 PM

Central Connecticut State

UCONN

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Sep 3rd, 12:00 PM

Delaware

Navy

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Sep 3rd, 12:30 PM

Richmond

Virginia

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Sep 3rd, 1:00 PM

Northern Iowa

Air Force

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Sep 3rd, 2:00 PM

Southeast Missouri State

Iowa State

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Sep 3rd, 2:30 PM

Bowling Green +3 -110

UCLA -3 -110

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Sep 3rd, 3:30 PM

Cincinnati (23) +7.5 -107

Arkansas (19) -7.5 -107

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Sep 3rd, 3:30 PM

Oregon (11) +16.5 -107

Georgia (3) -16.5 -107

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Sep 3rd, 3:30 PM

Arizona +10 -110

San Diego State -10 -110

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Sep 3rd, 3:30 PM

UTEP +39 -110

Oklahoma (9) -39 -110

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Sep 3rd, 3:30 PM

Bethune-Cookman

Miami-FL (16)

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Sep 3rd, 3:30 PM

North Dakota

Nebraska

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Sep 3rd, 3:30 PM

Houston (24) -6.5 -110

UTSA +6.5 -110

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Sep 3rd, 3:30 PM

Tulsa -1.5 -110

Wyoming +1.5 -110

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Sep 3rd, 3:30 PM

Norfolk State

Marshall

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Sep 3rd, 4:00 PM

Troy +21.5 -110

Ole Miss (21) -21.5 -110

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Sep 3rd, 4:00 PM

UC Davis

California

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Sep 3rd, 4:00 PM

BYU (25) -13 -110

USF +13 -110

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Sep 3rd, 5:00 PM

Nicholls State

South Alabama

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Sep 3rd, 5:30 PM

Texas State +11 -110

Nevada -11 -110

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Sep 3rd, 6:00 PM

Rice +33.5 -110

USC (14) -33.5 -110

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Sep 3rd, 6:00 PM

Middle Tennessee +4.5 -110

James Madison -4.5 -110

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Sep 3rd, 6:00 PM

Morgan State

Georgia Southern

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Sep 3rd, 6:00 PM

Florida Atlantic -1 -110

Ohio +1 -110

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Sep 3rd, 7:00 PM

Mercer

Auburn

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Sep 3rd, 7:00 PM

Utah (7) -1.5 -107

Florida +1.5 -107

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Sep 3rd, 7:00 PM

Miami-OH +20 -110

Kentucky (20) -20 -110

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Sep 3rd, 7:00 PM

Elon

Vanderbilt

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Sep 3rd, 7:00 PM

South Dakota

Kansas State

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Sep 3rd, 7:00 PM

Albany-NY

Baylor (10)

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Sep 3rd, 7:00 PM

Illinois State

Wisconsin (18)

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Sep 3rd, 7:00 PM

Massachusetts +31.5 -110

Tulane -31.5 -110

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Sep 3rd, 7:00 PM

Army +3 -110

Coastal Carolina -3 -110

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Sep 3rd, 7:00 PM

Liberty -4 -110

Southern Miss +4 -110

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Sep 3rd, 7:00 PM

Grambling State

Arkansas State

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Sep 3rd, 7:00 PM

Southeastern Louisiana

Louisiana-Lafayette

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Sep 3rd, 7:30 PM

Utah State +34.5 -106

Alabama (1) -34.5 -106

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Sep 3rd, 7:30 PM

Memphis +12.5 -110

Mississippi State -12.5 -110

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Sep 3rd, 7:30 PM

Georgia State +11 -110

South Carolina -11 -110

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Sep 3rd, 7:30 PM

Notre Dame (5) +13.5 -107

Ohio State (2) -13.5 -107

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Sep 3rd, 7:30 PM

SMU -7.5 -110

North Texas +7.5 -110

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Sep 3rd, 8:00 PM

Colgate

Stanford

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Sep 3rd, 8:00 PM

Louisiana-Monroe +37 -110

Texas -37 -110

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Sep 3rd, 8:00 PM

Murray State

Texas Tech

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Sep 3rd, 8:00 PM

Louisville -4 -110

Syracuse +4 -110

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Sep 3rd, 8:00 PM

Maine

New Mexico

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Sep 3rd, 9:30 PM

Idaho

Washington State

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Sep 3rd, 10:30 PM

Boise State +4 -110

Oregon State -4 -110

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Sep 3rd, 10:30 PM

Kent State +21.5 -110

Washington -21.5 -110

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