Sep 19, 2020; Pittsburgh, Pennsylvania, USA;  Syracuse Orange quarterback Rex Culpepper (17) looks to pass  against the Pittsburgh Panthers during the second quarter at Heinz Field. The Panthers won 21-10. Mandatory Credit: Charles LeClaire-USA TODAY Sports

Syracuse betting trends: Clemson beware big dog

Clemson better stay on its toes as they host over-matched Syracuse because the Orange have tripped up teams in years past when dealing with monster point spreads.

The year was 2007 and Syracuse was staring at the biggest point spread in school history – 37.5 at powerhouse Louisville, a team riding a 20-game win streak. But the Orange scored on the game’s first play and upset the Cardinals 38-35 behind QB Andrew Robinson.

On Saturday, they Orange lay 46.5 points (per BetRivers) while facing another powerhouse – the No. 1 ranked Clemson Tigers. So bettor beware, even if you don’t buy the straight-up upset. Clemson needs to win by more than six TDs to cover this spread.

Check out all the college football odds and matchup reports here.

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College football betting trends

Illinois @ Wisconsin – Matchup Stats

Illinois is 0-7 SU, 2-5 ATS in their last 7 games at Wisconsin.

Auburn -3.5 @ Ole Miss – Matchup Stats

Auburn is 9-3 ATS in their last 12 games at Mississippi.

Ole Miss lost 11 straight SU as home underdogs since 2014 season (2-8-1 ATS)

Ole Miss is 1-15 SU as underdogs past 16 games

Syracuse +46.5 @ Clemson – Matchup Stats

Orange have never been underdog of more than 37.5 points (a monumental upset when they won 38-35 at Louisville Sept. 22, 2007). If you can remember the game, then-Heisman candidate Brian Brohm (currently the QB Coach at Purdue) threw for 555 yards and still lost.

More NCAA wagering trends

OVER is 9-1 in TCU’s last 10 games as the underdog (they are +6.5 at home to Oklahoma)

South Carolina is 11-4 ATS in their last 15 road games (they are +6 at LSU)

Alabama hasn’t lost in October since Oct 4, 2014 at Ole Miss (they are -2 at Tennessee)

Alabama has played 5 straight OVERs when road favorites of 21 points or more

Nebraska is 1-20 SU in their last 21 games as the underdog (they are +26.5 at Ohio State)

Ohio State was favored by more than three TDs five times in 2019, each game played OVER the total (total is 68 at BetRivers)

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