Louisville Cardinals vs SMU Mustangs Betting Report

November 22, 2025, 12:00 pm | Gerald J. Ford Stadium
Louisville
Cardinals
7-3
SMU
Mustangs
7-3

Nov 22nd, 12:00 PM

FanDuel NFP Opening BetRivers SugarHouse NFP Consensus

Louisville

SMU

Spread
+3.5
-3.5
-110
-110
+1.5
-1.5
-110
-110
+3.5
-3.5
-105
-115
+3.5
-3.5
-105
-115
+3.5
-3.5
-105
-115
Total
50
o -105
u -115
50.5
o -112
u -110
48.5
o -115
u -105
48.5
o -115
u -105
49.5
o -110
u -110
Moneyline
+157
-180
+105
-139
+160
-192
+160
-192
+155
-190
Louisville Props
SMU Props
Odds to Win College Football Championship
Fanduel logo
Recent Form
Name Record ATS Offense Defense ATS Home ATS Away OU Record OU Home OU Away
Louisville 7-3 3-7 31.5 21.5 0-7 3-0 5-5 4-3 1-2
Southern Methodist 7-3 4-6 32.2 20.4 2-3 2-3 3-7 1-4 2-3
Football Betting Trends
SMU Mustangs
Southern Methodist is 4-1 ATS in its last 5 games
Southern Methodist is 4-8 ATS in its last 12 games
Southern Methodist is 5-1 SU in its last 6 games
The total has gone UNDER in 6 of Southern Methodist's last 8 games
Southern Methodist is 2-4 ATS in its last 6 games at home
Southern Methodist is 18-3 SU in its last 21 games at home
The total has gone UNDER in 4 of Southern Methodist's last 5 games at home
Louisville Cardinals
Louisville is 3-7 ATS in its last 10 games
Louisville is 10-3 SU in its last 13 games
The total has gone UNDER in 4 of Louisville's last 6 games
Louisville is 5-0 ATS in its last 5 games on the road
Louisville is 5-0 SU in its last 5 games on the road
The total has gone OVER in 4 of Louisville's last 6 games on the road
Power Stats
Yards Per Point
Name Offense Defense Differential
LOUIS 13.17 13.69 -0.53
SMU 12.64 20.21 -7.57
Yards Per Pass
Name Offense Defense Differential
LOUIS 10.55 10.32 0.23
SMU 12.12 11.92 0.2
Yards Per Rush
Name Offense Defense Differential
LOUIS 5.05 3.54 1.51
SMU 4.14 3.02 1.12
Team Comparison
  • LOUIS
  • 29.2
  • 23
  • 6.2
  • 230.3
  • 153.9
  • 198.8
  • 116.1
  • -0.1
  • name
  • offense
  • defense
  • differential
  • passing yards
  • rush yards
  • pass yds allwd
  • rush yds allwd
  • t/o diff
  • SMU
  • 32.7
  • 19.1
  • 13.6
  • 286.6
  • 127.2
  • 280.6
  • 105.2
  • -1.1


Team Standings
Louisville Cardinals
Name Record Home Away ATS ATS Home ATS Away Offense Defense Diff
Overall 7-3 4-3 3-0 3-7 0-7 3-0 31.5 21.5 10
Last 3 1-2 0-2 1-0 1-2 0-2 1-0 24.3 21.7 2.7
vs Conf 4-3 1-3 3-0 3-4 0-4 3-0 8.1 6.3 1.9
SMU Mustangs
Name Record Home Away ATS ATS Home ATS Away Offense Defense Diff
Overall 7-3 4-1 3-2 4-6 2-3 2-3 32.2 20.4 11.8
Last 3 2-1 1-0 1-1 2-1 1-0 1-1 27.7 15.3 12.3
vs Conf 5-1 3-0 2-1 4-2 2-1 2-1 0 0 0
Offense vs. Defense
Title Stat Rank Stat Rank
Away Team Overall Scoring vs Home Team Overall Defense 31.5 45 20.4 32
Away Team Road Passing vs Home Team Home Passing Defense 241 48 303 133
Away Team Road Rushing vs Home Team Home Rushing Defense 135.7 72 122.4 53
Home Team Overall Scoring vs Away Team Overall Defense 32.2 40 21.5 39
Home Team Home Passing vs Away Team Road Passing Defense 292.2 16 202 39
Home Team Home Rushing vs Away Team Road Rushing Defense 104.8 124 102.3 11
Head to Head
  • LOUIS
  • 0-1
  • 0-1
  • 1-0
  • 27
  • 132
  • 3.9
  • 35
  • 62.9
  • 329
  • 461
  • 1
  • name
  • record
  • ATS
  • OU
  • score
  • rush yds
  • yds / rush
  • att
  • comp %
  • pass yds
  • total yds
  • TO
  • SMU
  • 1-0
  • 1-0
  • 1-0
  • 34
  • 190
  • 5.4
  • 28
  • 78.6
  • 291
  • 481
  • 0


Head to Head Breakdown
Date Away Home Score Line OU ATY HTY
Oct 5, 24 SMU LOUIS 34-27 -7 O 55.5 481 461
Team Last 5 Games
Louisville Cardinals
Date Opponent Score Result Line ATS Result YDS For YDS Allwd TO Location
Nov 14, 25 CLEM 19-20 L -1.5/50.5 L/U 385 308 0 H
Nov 8, 25 CAL 26-29 L -18.5/49.5 L/O 351 427 1 H
Nov 1, 25 VTECH 28-16 W -10.5/52.5 W/U 371 240 1 A
Oct 25, 25 BC 38-24 W -25.5/54.5 L/O 504 360 0 H
Oct 17, 25 MIAMI 24-21 W 10.5/49.5 W/U 367 334 -3 A
SMU Mustangs
Date Opponent Score Result Line ATS Result YDS For YDS Allwd TO Location
Nov 8, 25 BC 45-13 W -10.5/54.5 W/O 574 390 -3 A
Nov 1, 25 MIAMI 26-20 W 8.5/50.5 W/U 388 433 -1 H
Oct 25, 25 WAKE 12-13 L -5.5/52.5 L/U 246 301 -2 A
Oct 18, 25 CLEM 35-24 W 3.5/50.5 W/O 429 352 0 A
Oct 11, 25 STAN 34-10 W -19.5/55.5 W/U 369 353 -2 H