Aug 29, 2021; Santa Clara, California, USA; San Francisco 49ers running back Raheem Mostert (31) runs the ball against the Las Vegas Raiders in the first quarter at Levi's Stadium. Mandatory Credit: Cary Edmondson-USA TODAY Sports

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49ers RB Raheem Mostert departs after knee injury

San Francisco 49ers running back Raheem Mostert was ruled questionable to return after a knee injury in the first quarter of Sunday’s opener on the road against the Detroit Lions.

After rushing for 20 yards on his first two carries, the oft-injured Mostert was immediately removed from the game after the injury replaced by Elijah Mitchell, who ran 38 yards for a touchdown in the second quarter on his third carry.

JaMychal added a 3-yard TD run later in the second quarter as the 49ers built a 21-10 lead.

Despite being deemed questionable to return, Mostert he was loosening up on the sideline shortly after being replaced.

49ers rookie Trey Sermon, a former Ohio State star running back, was among the club’s inactives for the game.

–Field Level Media

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