The Buffalo Bills will play host to the New England Patriots for the first time since Tom Brady departed to Tampa Bay. The Bills will open as 3.5 point favorites over the Patriots on Sunday, which hasn’t happened often the past 20 years.
The Patriots have won 15 of their last 16 games in Buffalo, and have simply dominated this rivalry. The Patriots should continue their dominance over the Bills, and cover the 3.5 point spread here. They are 15-6 ATS is 21 games as underdogs, but let’s see if these new Patriots are as good as the old Patriots in a dog role.
Patriots Bills Odds: Buffalo -3.5 Total 42.5 at BetRivers | Matchup ReportÂ