Sep 21, 2025; Santa Clara, California, USA; San Francisco 49ers defensive end Nick Bosa (97) on the field during warm ups prior to a game against the Arizona Cardinals during the first half at Levi's Stadium. Mandatory Credit: Cary Edmondson-Imagn Images

49ers star DE Nick Bosa (knee) to undergo testing

San Francisco 49ers standout defensive end Nick Bosa injured a knee during Sunday’s victory over the Arizona Cardinals and will undergo further evaluation.

San Francisco coach Kyle Shanahan said the seriousness of the injury isn’t yet known.

“No, we can’t rule anything out,” Shanahan said after the 16-15 victory. “They checked for ACL and stuff there. He was good with that, but we’re still not sure, so we gotta check with more things tonight and tomorrow.”

Bosa was injured in the first quarter while being double-teamed during an Arizona pass play. His knee bent awkwardly as he fell to the ground and he left the contest and didn’t return.

Bosa had two tackles and a forced fumble before departing.

Bosa, a five-time Pro Bowl selection, is in his seventh season with San Francisco. He was the NFL Defensive Player of the Year in 2022 when he recorded a career-high 18.5 sacks.

–Field Level Media

Jan 30, 2025; Orlando, FL, USA; AFC linebacker Joey Bosa of the Los Angeles Chargers during the Pro Bowl Skills Challenge at Nicholson Fieldhouse. Mandatory Credit: Kirby Lee-Imagn Images

Bills DE Joey Bosa injures calf, RB James Cook absent from OTAs

Buffalo Bills defensive end Joey Bosa likely will be out until training camp with a calf injury, coach Sean McDermott confirmed Tuesday.

McDermott said all players were present for OTAs except for running back James Cook, who is seeking a long-term contract extension.

Bosa, 29, signed a one-year, $12.6 million deal with the Bills earlier this offseason following nine seasons, 72 sacks and five Pro Bowl selections with the Los Angeles Chargers (2016-24).

Injuries have hampered the star pass rusher in recent years, as he played only five games in 2022 and nine in 2023. Last season, Bosa suited up for 14 contests, recording 22 tackles, five sacks and two forced fumbles. He generated 19 quarterback pressures and 13 quarterback hits.

Cook, 25, also was absent from voluntary workouts last month.

Entering the final year of his rookie deal, Cook has seen three teammates from his 2022 draft class earn four-year contract extensions this offseason: wide receiver Khalil Shakir, linebacker Terrel Bernard and cornerback Christian Benford.

Cook posted his second straight 1,000-yard season in 2024 while also tying the franchise record with 16 rushing touchdowns. In three seasons, he has rushed for 2,638 yards and 20 TDs.

Cook publicly has stated his desire to lock up a new contract. In February, he took to Instagram Live and pinned the comment “15 mill year” to the top of the feed, referring to his asking price of $15 million per year. That would make him the third-highest-paid running back behind Philadelphia’s Saquon Barkley ($20.6 million) and San Francisco’s Christian McCaffrey ($19 million).

–Field Level Media

Jan 11, 2025; Houston, Texas, USA; Los Angeles Chargers outside linebacker Joey Bosa (97) sacks Houston Texans quarterback C.J. Stroud (7) during the first quarter in an AFC wild card game at NRG Stadium. Mandatory Credit: Troy Taormina-Imagn Images

Chargers release OLB Joey Bosa after nine-year run

Joey Bosa is a free agent after he was released by the Los Angeles Chargers on Wednesday — a transaction that will save the team $25.36 million against the salary cap.

The 29-year-old outside linebacker is coming off the fifth Pro Bowl season of his nine-year career, all spent with the Chargers. He would have been due a $12.36 million bonus if he remained on the team’s roster on March 12.

Bosa racked up 72 sacks for the Chargers, the second-best total in franchise history. Leslie O’Neal, who played for the club from 1986-95, had 105.5 sacks.

The then-San Diego Chargers drafted Bosa out of Ohio State with the third overall pick in the 2016 draft, and he was an immediate star. He was chosen the NFL’s Defensive Rookie of the Year after registering 10.5 sacks, 41 tackles and a forced fumble in 12 games (11 starts) that year.

In 107 NFL games (93 starts), Bosa has 343 tackles, 17 forced fumbles and four fumble recoveries.

However, his availability has been spotty due to injuries. Bosa played a combined 14 games in 2022 and 2023, then just 14 (with nine starts) last year, when he notched five sacks and two forced fumbles.

–Field Level Media

Dec 15, 2024; Houston, Texas, USA; Miami Dolphins wide receiver Jaylen Waddle (17) is helped off the field during the second quarter against the Houston Texans at NRG Stadium. Mandatory Credit: Troy Taormina-Imagn Images

Dolphins WRs Jaylen Waddle, Tyreek Hill ailing for 49ers’ clash

Miami Dolphins receivers Jaylen Waddle and Tyreek Hill are both ailing as the team prepares for Sunday’s home game against the San Francisco 49ers.

Waddle (knee) was listed as doubtful on Friday’s injury report after missing all three practices this week. He was injured in the second quarter of last weekend’s 20-12 loss to the Houston Texans.

Hill is listed as questionable with a wrist injury that has bothered him all season. Hill has said he will consider getting the wrist surgically repaired after the season.

Hill has 67 receptions for a team-best 805 yards in 14 games this season. He has caught five touchdown passes.

Waddle has 54 catches this season for 700 yards and two touchdowns.

Miami ruled out long snapper Blake Ferguson (non-football illness) and listed receiver D’Wayne Eskridge (knee) as doubtful.

Also listed questionable were left tackle Terron Armstead (knee), right tackle Kendall Lamm (back) and linebackers Bradley Chubb (knee) and Cameron Goode (knee).

San Francisco will be without left tackle Trent Williams (ankle) and running back Isaac Guerendo (foot/hamstring). Questionable for the contest are defensive end Nick Bosa (hip/oblique), linebacker Dre Greenlaw (Achilles, knee) and defensive end Robert Beal Jr. (ankle).

–Field Level Media

Nov 17, 2024; Santa Clara, California, USA; San Francisco 49ers defensive end Nick Bosa (97) waits on the sidelines against the Seattle Seahawks in the third quarter at Levi's Stadium. Mandatory Credit: David Gonzales-Imagn Images

49ers star defensive end Nick Bosa to miss third straight game

San Francisco 49ers star defensive end Nick Bosa will miss his third straight game after being downgraded to out for Sunday’s contest against the Chicago Bears.

Bosa has been sidelined by hip and oblique injuries. He didn’t practice at all this week.

Bosa has seven sacks in 10 games. He won the NFL Defensive Player of the Year Award in 2022.

San Francisco activated safety Talanoa Hufanga (wrist) from injured reserve. He was limited in practice all week.

Hufanga tore ligaments in his wrist during a game against the Arizona Cardinals on Oct. 6.

Hufanga had also missed the first two games this season as he finished up rehab from an ACL injury. He injured his right knee against the Tampa Bay Buccaneers in November 2023.

The 49ers also placed leading rusher Jordan Mason (ankle) and safety George Odum (knee) on injured reserve. Mason has rushed for 789 yards and three touchdowns.

Earlier in the week, San Francisco placed running back Christian McCaffrey (knee) on IR. The 2023 NFL Offensive Player of the Year was hurt during last Sunday’s 35-10 loss to the Buffalo Bills.

Rookie Isaac Guerendo is now the 49ers’ top healthy back. He has a stellar 5.9 average per carry while rushing for 246 yards and two scores.

Also, offensive lineman Aaron Banks (concussion) was downgraded to out.

The 49ers (5-7) have lost three straight games and are in last place in the NFC West.

–Field Level Media

Nov 17, 2024; Santa Clara, California, USA; San Francisco 49ers quarterback Brock Purdy (13) throws a pass against the Seattle Seahawks in the second quarter at Levi's Stadium. Mandatory Credit: David Gonzales-Imagn Images

Injuries pile up, 49ers uncertain QB Brock Purdy can return Sunday

San Francisco 49ers quarterback Brock Purdy was limited with the right shoulder injury that sidelined him last week and there is growing concern about the long-term status of left tackle Trent Williams.

Wednesday’s practice was not the start to the NFL workweek head coach Kyle Shanahan had hoped after Purdy was unable to bounce back from a shoulder injury in Week 11. Brandon Allen started at Green Bay and the 49ers (5-6) lost 38-10 with the backup-turned-starter committing three turnovers.

Williams was reportedly spotted in the locker room with a knee scooter and is experiencing pain walking. He played through an ankle injury against the Seattle Seahawks Nov. 17.

Defensive end Nick Bosa (hip, oblique) also missed practice Wednesday, leaving the 49ers to spend the holiday plotting to play the Buffalo Bills (9-2) without the three Pro Bowlers again.

“I don’t know anyone who gets Thanksgiving off unless maybe you have a Monday night game. You just start a lot earlier and get the players out,” Shanahan said. “We cram everything in so the players get out, tries to be home with the family by 5. I usually get home by 7 and they’re all mad at me, then get back to red-zone (installation).”

The 49ers are in danger of a three-game losing streak for the first time since Oct. 2021.

Injuries have been a common thread since September when running back Christian McCaffrey was a surprise scratch with an Achilles injury for the opener. Wide receiver Brandon Aiyuk (ACL) is out for the season at a position dinged from top to bottom.

Star linebacker Fred Warner also is ailing and said Wednesday that he fractured a bone in his ankle on Sept. 29 against the New England Patriots. The game against the Bills will mark his eighth straight game playing with the injury.

“It’s something I deal with every game,” Warner said. “I get on that table before every game and get it shot up every single game just to be able to roll. But it’s not an excuse. It’s just what it is. That’s the NFL. You’re not going to be healthy. You’ve got to go out there, you’ve got to find ways to execute, to play at a high level and to win every single week.”

Shanahan wasn’t interested in injury talk. He said the 49ers have not played well in the past two weeks, and puts part of his focus on getting more out of the running game with snow in the forecast on Sunday night.

He’s not in agreement with pundits who doubt McCaffrey’s ability early into his return from injured reserve, with a per-carry average of 3.5 yards compared to 5.4 in 2023.

“The speculation on Christian is a little unfair to him,” Shanahan said. “Christian is playing very well. He’s playing his ass off. To think a guy who misses the entire offseason is going to come back and be the exact same the day he comes back would be unfair to any player in the world.”

San Francisco opened the 21-day practice window for linebacker Dre Greenlaw, who tore his Achilles in the Super Bowl in February. His return date is unclear.

–Field Level Media

Feb 5, 2024; Las Vegas, NV, USA; San Francisco 49ers defensive end Nick Bosa (97) during Super Bowl LVIII Opening Night at Allegiant Stadium. Mandatory Credit: Kirby Lee-USA TODAY Sports

For Nick Bosa, Super Bowl about a ring — and revenge

LAS VEGAS — Losing in the Super Bowl to the Kansas City Chiefs four seasons ago has never slipped the mind of San Francisco 49ers star Nick Bosa.

The defensive end said he documented his feelings and will break them out later this week as part of his preparation for the Sunday rematch.

“There are a couple recordings that I have,” Bosa said at Monday’s Super Bowl Opening Night. “I had some thoughts and I didn’t want to forget them, so they’re in my phone.”

Bosa and the 49ers had a 10-point lead past the midway point of the fourth quarter in Super Bowl LIV before Kansas City scored 21 straight points to post a 31-20 victory at Hard Rock Stadium in Miami Gardens, Fla.

Bosa scored one sack of Chiefs star quarterback Patrick Mahomes in that game and is eager for more.

“What stands out is very thin margins,” said Bosa, referring to Mahomes’ quick release and escape ability. “Very grateful for the opportunity against the same team. We have to make it count this time.”

Bosa and the 49ers figure to bring pressure with the Kansas City offense sometimes having issues against physical units.

Chiefs coach Andy Reid hasn’t forgotten the struggles of dealing with Bosa and the rest of San Francisco’s front seven four years ago.

“There were some running lanes early. They closed those up,” Reid said of the previous Super Bowl. “Their front — it starts with them. They’re really good, their front four. And then two of the most athletic linebackers in the league (in Fred Warner and Dre Greenlaw).”

Yet even with the 49ers’ four sacks in the game, Mahomes still made the San Francisco defense pay.

“There’s a few plays in the Super Bowl we look back at that were very big plays where he made plays with his legs,” Bosa said.

Bosa had 10.5 sacks this season after needing time to find his stride after a long holdout.

He agreed to a five-year, $170 million contract as the highest-paid defensive player in NFL history shortly before the season started.

“It’s definitely a weight off your back getting your second deal done and just having that out of the equation,” Bosa said. “It was a stressful time. I’m glad it’s over with.”

One season earlier, Bosa had a league-best 18.5 sacks and won NFL Defensive Player of the Year honors. He has 53.5 sacks in 68 regular-season games.

Bosa has 10 sacks in 11 postseason contests, including two in the NFC Championship Game last month when the 49ers rallied from a 17-point deficit to claim a 34-31 victory over Detroit.

Bosa isn’t the only key San Francisco defender looking to close the door on past demons.

Warner repeatedly replays the Super Bowl LIV loss in his mind. He intercepted a Mahomes pass in that game, but the fourth-quarter collapse is what’s at the forefront of his thoughts.

“The biggest thing I take away from that game is the game is never over until that clock hits triple zeros,” Warner said. “That’s the biggest takeaway.

“I remember guys on the sidelines in that fourth quarter real happy and excited about possibly becoming Super Bowl champions and things flipped on a dime real quick. (Kansas City) scoring 21 unanswered in about six minutes.

“That scar remains with me to this day.”

–Field Level Media

Nov 12, 2023; Inglewood, California, USA; Los Angeles Chargers wide receiver Keenan Allen (13) looks on during the first half against the Detroit Lions at SoFi Stadium. Mandatory Credit: Orlando Ramirez-USA TODAY Sports

Chargers rule out WR Keenan Allen, DE Joey Bosa

The Los Angeles Chargers have ruled out wide receivers Keenan Allen and Josh Palmer and pass-rusher Joey Bosa for Sunday’s game at the Denver Broncos.

The team announced the news Friday. Allen (heel) will miss his third straight game and Bosa (foot) will miss his sixth straight. Palmer sustained a concussion in last week’s 24-22 loss to the Buffalo Bills.

Allen, 31, leads the Chargers with 108 catches for 1,243 yards and seven touchdowns in 13 games.

Palmer, 24, has 32 receptions for 537 yards and two scores in nine games (five starts).

Bosa, 28, has recorded 6.5 sacks and 20 tackles in nine games (five starts) this season.

Linebacker Kenneth Murray (shoulder) and Tanner Muse (knee) and defensive tackle Nick Williams (shoulder) are doubtful for the Week 17 contest. Tight end Nick Vannett (back), cornerback Deane Leonard (heel) and guard Zion Johnson (knee) are questionable.

The Chargers (5-10) lost 24-7 to the Broncos (7-8) in the first meeting of the AFC West rivals in Week 14 in Inglewood, Calif.

–Field Level Media

Oct 16, 2023; Inglewood, California, USA;  Los Angeles Chargers linebacker Joey Bosa (97) rushes against Dallas Cowboys offensive tackle Tyron Smith (77) during the third quarter at SoFi Stadium. Mandatory Credit: Kiyoshi Mio-USA TODAY Sports

Chargers’ Joey Bosa says his left big toe is fractured

Los Angeles Chargers standout pass rusher Joey Bosa disclosed Friday that he has been playing with a fractured left big toe.

Bosa said the toe got stepped on in a Week 3 game against the Minnesota Vikings. He sat out the following week against the Las Vegas Raiders with hamstring and toe injuries.

Bosa told reporters that both ailments — the toe and hamstring — are healing and he’s good to go for Sunday’s game against the Kansas City Chiefs.

“The first couple weeks were tough,” Bosa said. “I got stepped on. Obviously, it was an accident.

“Definitely still sore in the toe but the hamstring is 100 percent. … Your toe gets stepped on all the time when you are in the trenches.”

Bosa was limited in practice on Wednesday and Thursday before being a full-go on Friday. He was not given a game status.

Bosa played in Monday’s 20-17 loss to the Dallas Cowboys but was limited to 30 snaps due to the two ailments. He has played just 77 snaps over the past three games.

“I’ve just got to manage it,” Bosa said of the toe. “Make sure I’m keeping it nice and taking care of it. But it shouldn’t be a problem anymore.”

Bosa, a four-time Pro Bowler, has three sacks this season to raise his career count to 63.5 over eight NFL seasons, all with the Chargers.

The Chargers ruled out four players on Friday — safety Alohi Gilman (heel), cornerback Deane Leonard (hamstring), defensive lineman Otito Ogbonnia (knee) and receiver Jalen Guyton (knee). Safety Derwin James Jr. (ankle) and linebacker Amen Ogbongbeminga (groin) are questionable.

Guyton and Ogbonnia are currently on injured reserve but the team opened their 21-day practice windows on Thursday.

–Field Level Media

Sep 24, 2023; Minneapolis, Minnesota, USA; Los Angeles Chargers linebacker Joey Bosa (97) sacks Minnesota Vikings quarterback Kirk Cousins (8) in the first quarter at U.S. Bank Stadium. Mandatory Credit: Brad Rempel-USA TODAY Sports

Chargers pass rusher Joey Bosa downgraded to doubtful vs. Raiders

Los Angeles Chargers edge rusher Joey Bosa was downgraded to doubtful for Sunday’s game against the visiting Las Vegas Raiders due to his hamstring and toe injuries.

Bosa was listed as questionable on Friday’s injury report.

Bosa didn’t participate in practice at all this week. The team has a bye week following the contest against the Raiders.

The four-time Pro Bowl selection has three sacks in three games this season. He has 63.5 in 87 games (80 starts) in eight seasons with the Chargers, the first in 2016 when the team was located in San Diego.

Star safety Derwin James Jr. (hamstring) also didn’t practice all week and is listed as doubtful. Standout running back Austin Ekeler (ankle) is doubtful and hoping to return after missing the previous two games.

The Chargers also placed center Corey Linsley and safety JT Woods (illness) on the non-football illness list and signed safeties Dean Marlowe and AJ Finley to the active roster. Linsley was diagnosed with a heart issue earlier this week and will miss at least four games.

Los Angeles also elevated receiver Keelan Doss and outside linebacker Andrew Farmer from the practice squad.

–Field Level Media