Oct 12, 2025; Tampa, Florida, USA; San Francisco 49ers quarterback Mac Jones (10) takes a snap during the first quarter against the Tampa Bay Buccaneers at Raymond James Stadium. Mandatory Credit: Nathan Ray Seebeck-Imagn Images

49ers’ Mac Jones to start again as Brock Purdy, Ricky Pearsall ruled out vs. Falcons

The San Francisco 49ers will again turn to backup quarterback Mac Jones with starter Brock Purdy out for Sunday’s matchup with the Atlanta Falcons, head coach Kyle Shanahan said Friday.

Purdy continues to recover from a lingering toe injury that he aggravated in Week 4. Jones, who has gone 2-2 as a starter this season, will make his fifth consecutive start after returning to full practice participation late in the week.

Meanwhile, Ricky Pearsall will miss his third straight game with a sprained knee.

The 49ers received better news elsewhere on offense, with tight end George Kittle cleared to return from a hamstring injury that had kept him sidelined since Week 1. Shanahan said Kittle will have “no pitch count” in his return.

“George has rehabbed really well, came back 100 percent, had a good week of practice,” Shanahan said.

Despite a rash of injuries to key players, including season-enders for defensive stars Nick Bosa and Fred Warner, San Francisco enters Week 7 with a 4-2 record and tied for first in the NFC West with the Los Angeles Rams and Seattle Seahawks.

Shanahan said the team hopes to have Purdy back “soon” after he practiced each day this week.

“He was able to get out there, throw more,” Shanahan said of Purdy on Friday. “Thought it was definitely a step further ahead than it was last week, so going in the right direction.”

–Field Level Media

Jan 5, 2025; Glendale, Arizona, USA; San Francisco 49ers quarterback Brock Purdy (left) with tight end George Kittle (85) against the Arizona Cardinals at State Farm Stadium. Mandatory Credit: Mark J. Rebilas-Imagn Images

49ers QB Brock Purdy, TE George Kittle return as limited practice participants

San Francisco 49ers coach Kyle Shanahan said quarterback Brock Purdy and tight end George Kittle will return to practice on Wednesday as limited participants.

Purdy has missed four of the past five games due to a turf toe injury initially sustained in the season-opening road win over the Seattle Seahawks on Sept. 7 and aggravated during a Sept. 28 home loss to the Jacksonville Jaguars.

Kittle, 32, has been on injured reserve since hurting his hamstring in the season opener and missed five games for the 49ers (4-2), who host the Atlanta Falcons on Sunday. With Kittle officially designated to return, he will have 21 days to practice and be activated to the 53-man roster or return to IR and be out for the season.

Purdy, 25, has thrown for 586 yards, four touchdowns and four interceptions on 73 passes. His replacement, Mac Jones, has been dealing with knee and oblique issues but still has started four games, going 3-1 and passing for 1,252 yards and six TDs with three picks.

Both were listed as limited for practice on Wednesday, with Shanahan saying, “Brock is more limited than Mac.”

For his career, Purdy has completed 67.4% of his passes for 10,104 yards and 68 touchdowns with 31 interceptions in 42 regular-season games, going 24-14 as a starter. He also has thrown for 1,343 yards, six TDs and one pick in six playoff games (all starts).

San Francisco used the 262nd and last overall pick of the 2022 NFL Draft to select Purdy in the seventh round. He was in the Pro Bowl the next season.

Kittle caught a 5-yard touchdown pass in the first quarter and had four receptions on four targets for 25 yards before exiting in the first half of the 49ers’ 17-13 win over the Seahawks.

He caught 78 passes for 1,106 yards and eight TDs last season, his eighth campaign with San Francisco since being a fifth-round draft pick in 2017. Kittle has four career 1,000-yard seasons as part of his career totals of 542 receptions for 7,405 yards and 46 TDs in 114 regular-season games (106 starts).

Kittle has another 33 receptions for 455 yards and two TDs in 12 playoff games (all starts). He is a two-time first-team All-Pro and six-time Pro Bowl selection.

He became the highest-paid tight end in NFL history in the offseason when he signed a four-year, $76.4 million extension ($19.1 million average) through 2029.

–Field Level Media

Sep 28, 2025; Santa Clara, California, USA; San Francisco 49ers quarterback Brock Purdy (13) gestures during the first quarter against the Jacksonville Jaguars at Levi's Stadium. Mandatory Credit: Darren Yamashita-Imagn Images

49ers QB Brock Purdy (toe) holding out hope he can play Thursday

With a game against the NFC West rival Los Angeles Rams coming up Thursday, San Francisco 49ers quarterback Brock Purdy (toe) said he has not been ruled out from playing in it.

Purdy missed Weeks 2 and 3 due to a toe injury but returned Sunday. The fourth-year quarterback told reporters following the 49ers’ 26-21 loss to the Jacksonville Jaguars that he didn’t have any issues during the game. But as the evening passed, he said pain began to set in, prompting a call to head coach Kyle Shanahan to inform him of that.

Purdy was listed as a non-participant in practice each of the past two days, and he’s running out of time to practice given the short turnaround. It doesn’t help Purdy that San Francisco had just a walk-through Tuesday and have no more full practices before playing Thursday night.

“If I can play this game, I want to play,” Purdy said. “Obviously, I want to get right and get healthy and everything, but we need to win this game against the Rams. So that’s how I’m looking at it.”

Shanahan said Tuesday the choice on who to start, Purdy or backup Mac Jones, will come down to how effective the team feels Purdy can be.

“It’ll come down to do we feel he could play and to 100 percent of his ability, and do we feel that he can protect himself with it?” Shanahan said.

Both the 49ers and Rams are 3-1 heading into their key divisional matchup in Los Angeles on Thursday night. While the Rams have played all non-NFC West opponents thus far, the Niners beat the other two NFC West foes, the Seahawks and Cardinals.

Purdy added that he didn’t aggravate the injury on any one play; it was just a build-up after playing in the game. He also said it feels better than when he first hurt it in Week 1 vs. the Seahawks.

Purdy has completed 48 of 73 passes for 586 yards, with four touchdowns and four interceptions, in his two games as a starter. Jones is 53-of-80 passing for 563 yards, with four scores and one pick while going 2-0 in his two games.

Also worth noting is the Niners’ pass-catching corps has been short-handed — tight end George Kittle (hamstring) and receiver Brandon Aiyuk (knee) have been out — and that could get even worse this week, as receivers Jauan Jennings (ankle) and Ricky Pearsall (knee) did not practice Tuesday.

–Field Level Media

Sep 28, 2025; Santa Clara, California, USA; San Francisco 49ers quarterback Brock Purdy (13) runs the ball during the first half against the Jacksonville Jaguars at Levi's Stadium. Mandatory Credit: Kyle Terada-Imagn Images

49ers QB Brock Purdy hurting again, could miss TNF vs. Rams

49ers quarterback Brock Purdy’s return to the starting role might be brief.

Purdy re-injured his toe in San Francisco’s 26-21 loss to the Jaguars on Sunday, leaving his availability up in the air on a short week, head coach Kyle Shanahan said Monday.

The 49ers (3-1) are set to visit the Los Angeles Rams (3-1) on Thursday night, a critical early test in the tightly packed NFC West.

Purdy played in the 26-21 defeat on Sunday afternoon and told reporters afterward that he felt fine. But Shanahan said Monday morning that Purdy had called him on Sunday night and said the injury, a form of turf toe, again was bothering him.

The quarterback is expected to be evaluated on Monday afternoon, Shanahan said.

“Hopefully, we’ll find out more later today, but any time guys are sore and hurting on a Monday, you usually don’t stress too much about it,” Shanahan said. “But anytime you have a Thursday game, it’s a totally different element. So, I’m concerned with anybody who’s not totally healthy at this moment, but we’ll have to get more information on that later today to really have a clue of what to speculate.”

Purdy was injured during the season-opening 17-13 road victory over the Seattle Seahawks. He passed for 277 yards, two touchdowns and two interceptions.

The 25-year-old sat out wins over the New Orleans Saints and Arizona Cardinals to rest his foot.

His replacement, Mac Jones, sustained a knee sprain and was limited in practice last week. Purdy went from limited early in the week to being cleared to play against Jacksonville.

Purdy was 22-of-38 passing for 309 yards, two touchdowns and two interceptions and also lost a fumble. He said the toe wasn’t an issue, but Purdy acknowledged that his mechanics might have been off, resulting in a few high throws.

“I think just getting back out there and throwing and getting into a rhythm, being down two weeks, coming back and feeling out my body and everything, obviously how my toe feels,” he said.

“Honestly, I don’t know the answer to that,” he said of the toe injury’s impact. “But, obviously, I’m going to watch this film, look at my mechanics and be real with myself and try to fix that.”

Purdy is a combined 48 of 73 (65.8 percent) for 586 yards, four TDs and four interceptions with a 78.8 quarterback rating in his two games. For his career, he is a 67.5-percent passer, with 10,104 yards, 68 TDs and 31 picks in 42 regular-season games (38 starts) and a 24-14 record.

Shanahan also said that wide receiver Ricky Pearsall could miss the next game with an ailing right knee. He was hurt attempting to make a catch in bounds and left the game early on Sunday.

“I was testing out my knee,” Pearsall said. “I fell pretty hard on that play on the sideline, trying to keep my feet in bounds, and I fell pretty hard on my knee. I was just feeling pain and a little bit of instability. I wasn’t trying to mess with it.”

Shanahan does not think that Pearsall has a long-term injury from the initial evaluation but pointed to a possible sprain.

“They’re thinking more of a minor PCL or something like that is what our guess is, just landing on it hard,” Shanahan said. “Hopefully, it won’t be too bad. Obviously, a huge concern with the Thursday night game and stuff, but we’re not expecting it to be too bad.”

Pearsall, 25, has 20 receptions on 29 targets for 327 yards in starting all four games.

San Francisco wide receiver Jauan Jennings injured his ribs on Sunday in his return to the lineup from injury. He also will be further evaluated on Monday.

Jennings, 28, has played in three games this season — all starts — and has nine catches on 19 targets for 129 yards and one touchdown. He missed the Week 3 win over Arizona because of ankle and shoulder issues.

–Field Level Media

Sep 7, 2025; Seattle, Washington, USA; San Francisco 49ers quarterback Brock Purdy (13) runs the ball during the first half against the Seattle Seahawks at Lumen Field. Mandatory Credit: Joe Nicholson-Imagn Images

49ers QBs Brock Purdy (toe), Mac Jones (knee) both ailing

The San Francisco 49ers are assessing their quarterback situation ahead of a Week 4 matchup against the Jacksonville Jaguars with both Brock Purdy and Mac Jones ailing.

Purdy returned to practice Wednesday after missing the past two games with a toe injury. Jones started the past two games for San Francisco but is now dealing with a knee injury that he aggravated during Sunday’s victory over the Arizona Cardinals.

In another injury concern, wide receiver Ricky Pearsall is dealing with his own knee discomfort and missed practice Wednesday.

Both quarterbacks are expected to be limited in practice to start the week. The 49ers’ third-string quarterback is Adrian Martinez, who has never taken an NFL snap.

Purdy was 26 of 35 for 277 yards and two touchdowns with two interceptions in the team’s season-opening victory over the Seattle Seahawks. Jones has gone a combined 53 of 80 for 563 yards, four TDs and one interception over victories the following two weeks.

Purdy, 25, has completed 67.8 percent of his passes in 41 games (37 starts) over four seasons for the 49ers with 66 TDs and 29 interceptions.

Jones, 27, has completed 65.9 percent of passes with 58 TDs and 45 interceptions in 54 games (51 starts) over five seasons for the New England Patriots (2021-23), Jacksonville Jaguars (2024) and 49ers.

Pearsall, 25, has 16 receptions for 281 yards in three games of his second NFL season. In 14 career games (seven starts) he has 47 receptions for 681 yards and three TDs.

Another wide receiver, Jauan Jennings (ankle, shoulder) was set to miss practice Wednesday after not playing last Sunday.

–Field Level Media

Sep 7, 2025; Seattle, Washington, USA; San Francisco 49ers quarterback Brock Purdy (13) reacts following a failed third down play against the Seattle Seahawks during the fourth quarter at Lumen Field. Mandatory Credit: Joe Nicholson-Imagn Images

49ers downgrade Brock Purdy, Jauan Jennings to out vs. Cardinals

San Francisco 49ers quarterback Brock Purdy and wide receiver Jauan Jennings have been downgraded from questionable to out and will not play Sunday against the Arizona Cardinals.

Both teams enter the NFC West game in Santa Clara, Calif., at 2-0.

Purdy came away from the season-opening win against the Seattle Seahawks with toe and left shoulder injuries, his toe being the bigger concern. He sat out Week 2 while backup Mac Jones completed 26 of 39 passes for 279 yards, three touchdowns and no interceptions to guide the Niners to a 26-21 victory at New Orleans.

San Francisco coach Kyle Shanahan said earlier in the week that he did not expect Purdy to play but left the door ajar. As a precaution, the team activated quarterback Adrian Martinez from the practice squad on Saturday.

Jennings had been questionable due to ankle and shoulder injuries. Against the Saints, he caught five passes for 89 yards and a touchdown.

–Field Level Media

Sep 7, 2025; Seattle, Washington, USA; San Francisco 49ers quarterback Brock Purdy (13) reacts after the game against the Seattle Seahawks during the fourth quarter at Lumen Field. Mandatory Credit: Joe Nicholson-Imagn Images

Early return? 49ers QB Brock Purdy limited in practice Wednesday

San Francisco quarterback Brock Purdy was a limited participant in practice Wednesday and has a chance to play on Sunday, 49ers coach Kyle Shananah said.

Toe and shoulder injuries kept Purdy on the sideline for San Francisco’s 26-21 win at New Orleans last week. He has a form of turf toe and was expected to miss multiple weeks. In a spot start, backup Mac Jones completed 26 of 39 passes for 279 yards and three touchdowns without an interception.

The 49ers (2-0) play their home opener on Sunday against the Arizona Cardinals (2-0).

Purdy, 25, is nursing left shoulder and toe ailments after completing 26 of 35 passes for 277 yards, two TDs and two interceptions in the season-opening 17-13 victory at the Seattle Seahawks.

San Francisco placed starting left guard Ben Bartch on injured reserve on Wednesday due to a high ankle sprain. The team promoted tight end Brayden Willis to the active roster and signed offensive lineman Brandon Parker to the practice squad.

Shanahan also said guard Spencer Burford (knee), defensive end Yetur Gross-Matos (knee), fullback Kyle Juszczyk (concussion) and safety Siran Neal (concussion) will sit out practice.

Wednesday is a scheduled rest day for defensive end Nick Bosa, running back Christian McCaffrey and left tackle Trent Williams.

–Field Level Media

Sep 7, 2025; Seattle, Washington, USA; San Francisco 49ers quarterback Brock Purdy (13) runs the ball during the first half against the Seattle Seahawks at Lumen Field. Mandatory Credit: Joe Nicholson-Imagn Images

49ers QB Brock Purdy out; Mac Jones to start vs. Saints

San Francisco 49ers quarterback Brock Purdy did not practice this week while nursing left shoulder and toe ailments, and on Friday he was ruled out of Sunday’s game at the New Orleans Saints.

Starting under center in Purdy’s place will be Mac Jones, who took all the first-team reps in practice on Wednesday, Thursday and Friday ahead of his first start with the 49ers. The 2021 first-round pick (No. 15 overall) of the New England Patriots signed a two-year deal for $7 million in March.

“Mac’s been awesome,” head coach Kyle Shanahan told reporters this week. “Our team really believes in him.”

As for Purdy, general manager John Lynch on Thursday told KNBR radio that the fourth-year signal-caller is “week to week.”

“Brock is doing well,” Lynch told KNBR. “He’s doing a nice job, doing everything he can to get back out there as soon as possible. … But that’s where we’re at, on a week-to-week deal.”

Shanahan told reporters this week that Purdy’s toe injury could keep him for multiple weeks.

Purdy, 25, completed 26 of 35 passes for 277 yards with two TDs and two picks in the season-opening 17-13 victory at Seattle. The 2023 Pro Bowl selection is 24-13 as the starter since being selected with the 262nd and final pick in the 2022 NFL Draft.

Jones, who turned 27 last week, played 10 games with the Jacksonville Jaguars in 2024 after three seasons with the Patriots.

Jones is 20-29 in his career as a starter, completing 65.9 percent of his passes for 10,590 yards with 54 touchdowns and 44 interceptions. He made the Pro Bowl after his rookie campaign.

Adrian Martinez, who has not played in an NFL game, will be elevated to the active roster to back up Jones. Martinez, 25, served as a backup for the New York Jets for one game last season. He’s also spent time with the Detroit Lions.

Already without star tight end George Kittle, who was placed on injured reserve earlier this week with a hamstring injury, the 49ers may be without Jauan Jennings (shoulder) and left tackle Trent Williams (knee), who are questionable. Both missed practice on Wednesday and Thursday but did light work on Friday.

–Field Level Media

Sep 7, 2025; Seattle, Washington, USA; San Francisco 49ers quarterback Brock Purdy (13) runs the ball during the first half against the Seattle Seahawks at Lumen Field. Mandatory Credit: Joe Nicholson-Imagn Images

Report: 49ers QB Brock Purdy (toe) out 2-5 weeks

San Francisco 49ers quarterback Brock Purdy will be sidelined for 2-5 weeks with a “turf toe variant,” NFL Network reported Thursday.

Head coach Kyle Shanahan on Wednesday called Purdy a “long shot” to play Sunday at New Orleans due to injuries to his toe and left shoulder.

Former first-round draft pick Mac Jones is expected to replace Purdy and will make his 50th career start in Week 2 against the Saints.

“Mac knows how to play the position, sees the field well,” Shanahan said. “Tough guy. He’ll hang in there and deliver the ball where it needs to go.”

Jones, who turned 27 last week, played 10 games with the Jacksonville Jaguars in 2024 after three seasons with the New England Patriots, who drafted him 15th overall in 2021.

Jones is 20-29 in his career as a starter, completing 65.9 percent of his passes for 10,590 yards with 54 touchdowns and 44 interceptions. He made the Pro Bowl after his rookie campaign in 2021.

Purdy, 25, completed 26 of 35 passes for 277 yards with two TDs and two picks in the season-opening 17-13 victory at Seattle. The 2023 Pro Bowl selection is 24-13 as the starter since being selected with the 262nd and final pick in the 2022 NFL Draft.

The third quarterback on the San Francisco depth chart is rookie Kurtis Rourke, a seventh-round pick out of Indiana.

–Field Level Media

Sep 7, 2025; Seattle, Washington, USA; San Francisco 49ers quarterback Brock Purdy (13) runs the ball during the first half against San Francisco 49ers at Lumen Field. Mandatory Credit: Joe Nicholson-Imagn Images

49ers QB Brock Purdy ‘long shot’ for Week 2; Mac Jones could start

49ers quarterback Brock Purdy is a “long shot” to play Sunday with left shoulder and toe injuries, and he’s not San Francisco’s only injury worry.

“I think it’s a long shot,” 49ers coach Kyle Shanahan said Wednesday of Purdy’s status for Week 2 at New Orleans on Sunday.

Shanahan said it’s “possible” Purdy will miss multiple weeks because of the severity of his toe injury. Shanahan said the injury is on the bottom of Purdy’s foot between the big toe and second toe, all but eliminating his mobility.

Former first-round pick Mac Jones, drafted 15th overall by the New England Patriots in 2021, slides into the starting spot with the 49ers trying to sort through who else could be available. Tight end George Kittle, a six-time Pro Bowl selection, won’t play in at least the next four games after going on injured reserve because of a hamstring injury in the season-opening 17-13 victory over the Seattle Seahawks.

“Mac knows how to play the position, sees the field well,” Shanahan said. “Tough guy. He’ll hang in there and deliver the ball where it needs to go.”

“I don’t know who has a faster 40. Brock, I’d say, is a little better scrambler.”

Jones, who turned 27 last Friday, played 10 games with the Jacksonville Jaguars in 2024. He is 20-29 in his career as a starter, and also lost in his lone postseason game (2021 with New England). The 49ers took a “very close” look at Jones coming out of Alabama in 2021, when they used the No. 3 overall pick on quarterback Trey Lance.

Purdy, running back Christian McCaffrey, left tackle Trent Williams and wide receiver Jauan Jennings were not available to practice on Wednesday. McCaffrey (calf) and Williams (knee) were already scheduled for a veteran rest day. Jennings left last week’s win at Seattle with a shoulder injury.

“It’s a huge challenge this week,” Shanahan said. “Hopefully, we keep getting better.”

–Field Level Media