October 4, 2020; Santa Clara, California, USA; San Francisco 49ers cornerback K'Waun Williams (24) during the third quarter against the Philadelphia Eagles at Levi's Stadium. Mandatory Credit: Kyle Terada-USA TODAY Sports

49ers CB Williams suspended two games for PED violation

San Francisco 49ers cornerback K’Waun Williams was suspended for two games by the NFL on Tuesday for violating the league’s policy on performance-enhancing substances.

Depending on the status of an ankle injury, the earliest Williams will be eligible to play after the suspension is when the 49ers host the Washington Football Team on Dec. 13.

Williams wasn’t expected to play in San Francisco’s next two games after suffering a high ankle sprain against the Green Bay Packers on Nov. 5.

The 29-year-old Williams has 14 tackles and one sack in six games (three starts) this season.

The 49ers also opened the 21-day practice window for running backs Raheem Mostert and Jeff Wilson Jr. — both are on injured reserve after sustaining ankle injuries. It is possible Mostert could play against the Los Angeles Rams on Sunday.

Mostert has a team-best 303 rushing yards despite playing in just four games. Wilson has 163 yards rushing in six games.

–Field Level Media

October 11, 2020; Santa Clara, California, USA; San Francisco 49ers running back Raheem Mostert (31) is tackled by Miami Dolphins cornerback Xavien Howard (25) and strong safety Bobby McCain (28) during the second quarter at Levi's Stadium. Mandatory Credit: Kyle Terada-USA TODAY Sports

49ers’ Mostert (ankle) out against Saints

San Francisco running back Raheem Mostert will miss Sunday’s game against the New Orleans Saints, as he’ll remain on injured reserve with a high ankle sprain, 49ers coach Kyle Shanahan said Wednesday.

Mostert could return as early as Nov. 29, when the 49ers travel to play the Rams in Los Angeles. The 49ers have a bye next week.

Mostert landed on IR after suffering his injury in Week 6 against the Rams. The injury halted what had been a stellar start to the season for Mostert, who had 453 yards, including 303 rushing, and two touchdowns.

With Tevin Coleman (knee) also expected to miss this week, Jerick McKinnon and JaMycal Hasty will likely continue to split time in the backfield until Mostert’s return.

–Field Level Media

October 11, 2020; Santa Clara, California, USA; San Francisco 49ers running back Raheem Mostert (31) is tackled by Miami Dolphins outside linebacker Kamu Grugier-Hill (51) during the fourth quarter at Levi's Stadium. Mandatory Credit: Kyle Terada-USA TODAY Sports

49ers place RB Mostert (ankle) on IR

The San Francisco 49ers placed running back Raheem Mostert on injured reserve Saturday due to a sprained left ankle.

Mostert must miss at least three games before he’s eligible to return.

The postseason hero from last season missed two games earlier this season with a different ankle injury.

Mostert has rushed for 303 yards and one touchdown on 51 carries and also has 11 receptions for 150 yards and one score this season.

Mostert etched his name into team lore in January when he rushed for a franchise-record 220 yards and scored four touchdowns as the 49ers pummeled the Green Bay Packers 37-20 in the NFC Championship Game.

Jerick McKinnon (211 rushing yards, four total touchdowns) will be the team’s lead running back for Sunday’s game against the New England Patriots.

San Francisco also activated safeties Johnathan Cyprien and Jared Mayden from the practice squad. Receiver Jauan Jennings was placed on the practice squad injured reserve list.

The 49ers activated Cyprien and Mayden because starting safeties Jaquiski Tartt (groin) and Jimmie Ward (quadriceps) will miss Sunday’s game.

–Field Level Media

September 13, 2020; Santa Clara, California, USA; San Francisco 49ers quarterback Jimmy Garoppolo (10) before the game against the Arizona Cardinals at Levi's Stadium. Mandatory Credit: Kyle Terada-USA TODAY Sports

49ers unsure if QB Garoppolo will be available vs. Dolphins

San Francisco 49ers quarterback Jimmy Garoppolo and running back Raheem Mostert were back on the practice field Wednesday for the first time since sustaining injuries in Week 2 against the New York Jets.

Both Garoppolo (ankle) and Mostert (knee) were listed as limited participants in Wednesday’s workout.

San Francisco coach Kyle Shanahan was noncommittal on whether Garoppolo would return for the team’s Sunday game against the Miami Dolphins.

Nick Mullens started the past two games with Garoppolo sidelined but isn’t a sure bet to start against Miami if Garoppolo can’t play. Shanahan could go with C.J. Beathard, who finished San Francisco’s 25-20 loss to the Philadelphia Eagles on Sunday.

But Shanahan wasn’t in a revealing mood. In fact, he made it clear he wants to keep the possible starter a secret.

“I’m going to hold that just because there is a difference between them, and if Jimmy can’t go, I’d like Miami to find that out on Sunday,” Shanahan said. “But I’ve decided that. We’ll get both of them reps because both of them do have to be ready in case Jimmy doesn’t go.”

Mullens completed 18 of 26 passes for 200 yards, one touchdown, two interceptions and a lost fumble before being pulled against the Eagles. Beathard connected on 14 of 19 passes for 138 yards.

Mostert, a postseason hero last season, will have to show progress during the week. Shanahan was skeptical Monday that his top runner would play against Miami.

Jerick McKinnon, who produced 54 yards and a touchdown on 14 carries against the Eagles, will be prepared to be the main back against the Dolphins.

Receivers Dante Pettis (knee) and Trent Taylor (ankle), cornerback Ahkello Witherspoon (hamstring) and linebacker Dre Greenlaw (quadriceps) also were limited practice participants.

Sitting out practice were cornerbacks Emmanuel Moseley (concussion) and Dontae Johnson (groin) as well as safety Jimmie Ward (wrist).

Also, Shanahan confirmed that defensive end Nick Bosa and defensive tackle Solomon Thomas have both undergone their season-ending ACL surgeries.

–Field Level Media