Sep 17, 2023; Glendale, Arizona, USA; Arizona Cardinals safety K'Von Wallace (22) tackles New York Giants running back Saquon Barkley (26) during the first half at State Farm Stadium. Mandatory Credit: Joe Camporeale-USA TODAY Sports

Giants RB Saquon Barkley (ankle) ruled out vs. 49ers

New York Giants star running back Saquon Barkley has been ruled out of Thursday’s road game against the San Francisco 49ers due to a sprained ankle.

Giants coach Brian Daboll initially told reporters on Tuesday that Barkley would be a game-time decision against the 49ers (2-0). On Wednesday, the team’s injury report listed Barkley as out, along with offensive linemen Andrew Thomas (hamstring) and Ben Bredeson (concussion) as well as linebacker Azeez Ojulari (hamstring).

Barkley and Bredeson did not practice on Wednesday, while Thomas, Ojulari joined wide receiver Wan’Dale Robinson (knee) and linebacker Micah McFadden (neck) in being limited. Robinson and McFadden are listed as questionable to face San Francisco.

Barkley, 26, hurt his right ankle during the Giants’ game-winning drive in a 31-28 road win over the Arizona Cardinals. He took a 2-yard carry up the middle and appeared to get his ankle caught under Arizona linebacker Krys Barnes with 1:08 left in the game.

Through two games, Barkley has rushed for 114 yards and one touchdown on 29 carries and caught nine passes for 41 yards and another score for the Giants (1-1).

Barkley missed time with ankle injuries in 2019 and 2021. His 2020 season was also cut short due to a torn ACL in Week 2.

Running back Matt Breida will receive increased playing time in the absence of Barkley. Breida, 28, carried the ball 54 times for 220 yards (4.1 yards per carry) in 17 games with the Giants last season.

–Field Level Media

Mar 1, 2023; Indianapolis, IN, USA; Louisiana State linebacker B J Ojulari (LB20) speaks to the press at the NFL Combine at Lucas Oil Stadium. Mandatory Credit: Trevor Ruszkowski-USA TODAY Sports

Cardinals activate BJ Ojulari from PUP

The Arizona Cardinals activated second-round draft pick BJ Ojulari (knee) from the physically unable to perform list on Monday.

The 21-year-old edge rusher has been on the PUP list since the start of training camp but was cleared to resume football work.

The Cardinals selected Ojulari with the 41st pick in this year’s draft out of LSU. He will compete for one of Arizona’s starting edge spots.

Ojulari played in 31 games in three years at LSU, logging 128 total tackles (78 solo), 16.5 sacks and two forced fumbles.

–Field Level Media

New York Giants wide receiver Sterling Shepard (3) jokes around during organized team activities (OTAs) at the training center in East Rutherford on Thursday, May 19, 2022.

Nfl Ny Giants Practice

Sterling Shepard active, Kayvon Thibodeaux inactive for Giants

New York Giants wide receiver Sterling Shepard was active for Sunday’s season opener against the host Tennessee Titans, while rookie outside linebacker Kayvon Thibodeaux was among the team’s inactives.

Shepard, who is returning from a torn Achilles tendon, returned to practice just two weeks ago and was activated from the physically unable to perform list on Aug. 24.

He declared himself “ready to go” for the Tennessee game, but Giants coach Brian Daboll said Shepard, Thibodeaux (knee), pass-rusher Azeez Ojulari (calf) and defensive back Dane Belton (clavicle) would all be game-time decisions.

Ojulari and Belton were inactive for New York along with Thibodeaux, the fifth overall pick in April’s draft whose NFL debut will have to wait at least one more week.

Running back Antonio Williams, cornerback Justin Layne, offensive lineman Tyre Phillips and wide receiver Darius Slayton were the Giants’ other inactives.
The Titans kept cornerback Lonnie Johnson, offensive tackle Jamarco Jones, defensive tackle Naquan Jones, running back Julius Chestnut and outside linebacker Derrek Tuszka inactive.

–Field Level Media

New York Giants wide receiver Sterling Shepard (3) makes one-handed catches as Kadarius Toney (89) looks on during organized team activities (OTAs) at the training center in East Rutherford on Thursday, May 19, 2022.

Nfl Ny Giants Practice

Giants WR Sterling Shepard (Achilles) begins camp on PUP

Wide receiver Sterling Shepard is one of three members of the New York Giants who began training camp on the physically unable to perform list.

Center Nick Gates (leg) and tackle Matt Peart (knee) also were placed on the PUP list as Giants camp opened Tuesday, and outside linebacker Azeez Ojulari (hamstring) is on the non-football injury list.

Shepard tore his left Achilles during Week 15 of the 2021 season. In his sixth NFL season, all with New York, he played a career-low seven games (six starts) and caught 36 passes for 366 yards and a touchdown.

In 72 career games (70 starts), Shepard has recorded 349 receptions for 3,884 yards and 21 touchdowns. Eight of those touchdowns came in his rookie year of 2016.

Ojulari’s hamstring injury occurred while training away from the Giants’ facility, The Athletic reported, but it isn’t considered serious.

The Giants’ second-round pick of the 2021 draft had eight sacks and a forced fumble as a rookie.

–Field Level Media