49ers QB Brock Purdy could return to starting role vs. Cardinals

The San Francisco 49ers plan to push Brock Purdy aggressively in practice this week with the hope he will start Sunday’s road game against the Arizona Cardinals.

Purdy last played in Week 4 when he aggravated a toe injury during a loss to the Jacksonville Jaguars. He initially hurt the toe in the season-opening win over the Seattle Seahawks and sat out the following two weeks.

Purdy, 25, was limited in practice Wednesday but also was taking repetitions with the first-team offense.

“If he takes a big step forward this week, like he did last week, then he should have a good chance to play,” 49ers coach Kyle Shanahan told reporters on Wednesday.

Mac Jones, 27, has started the last six games for San Francisco (6-4) while Purdy was sidelined.

Meanwhile, Purdy has been bogged down with his ailment and the 49ers considered making him the No. 2 signal caller in Week 9 against the New York Giants before leaving him inactive and going with Adrian Martinez as the backup.

The 49ers also made Purdy inactive in last weekend’s 42-26 home loss to the Los Angeles Rams.

Purdy has passed for 10,104 yards and 68 touchdowns against 31 interceptions in 42 regular-season games (38 starts) in four seasons with San Francisco. He was the last pick of the 2022 NFL Draft and helped the 49ers reach the NFC Championship Game as a rookie and the Super Bowl in the 2023 season.

Jones completed 33 of 39 passes for 319 yards, three touchdowns and one interception against the Rams.

Overall, Jones is 5-3 as the San Francisco starter.

Jones has passed for 2,151 yards, 13 touchdowns and six interceptions in eight games this season.

Also, 49ers wideout Ricky Pearsall (knee) is expected to return from a six-game absence. The 2024 first-round selection has 20 receptions for 327 yards in four games this season.

–Field Level Media

Sep 28, 2025; Santa Clara, California, USA; San Francisco 49ers quarterback Brock Purdy (13) after the game against the Jacksonville Jaguars at Levi's Stadium. Mandatory Credit: Darren Yamashita-Imagn Images

Injury to 49ers QB Brock Purdy (toe) could linger all season

San Francisco quarterback Brock Purdy will be dealing with his right big toe injury the rest of the season, 49ers coach Kyle Shanahan said after Sunday’s 34-24 road victory over the New York Giants.

The contest against New York marked the fifth in a row that Purdy missed. There was optimism he would be available against the Giants because he was listed as questionable and wasn’t ruled out for the game as in previous weeks.

But when the team turned in its pregame list of inactives, Purdy’s name was on it.

“We’re trying to ease Brock out there in the practice stuff, but anytime you’re dealing with his turf toe, it’s something that probably won’t fully go away all year regardless of when he comes back,” Shanahan said. “He’s going to always have to deal with a little bit. … So it’s really about just assessing when’s the best time to come back that you have to deal with it the least. It’s a little bit of a tricky decision.”

Shanahan said Purdy “wasn’t that close” to being active Sunday despite being listed as questionable. Adrian Martinez served as the No. 2 quarterback behind Mac Jones.

“I just want to make sure he gets 100% better and won’t put him out there too early,” Shanahan said. “Thought about it as a possible backup or emergency, but I think the more time we get, the better.”

Purdy was initially hurt during the season-opening 17-13 victory over against the Seattle Seahawks and missed the next two games. He aggravated the injury during a 26-21 home loss against the Jacksonville Jaguars in Week 4.

Jones has started seven games and San Francisco (6-3) has won five of them. He passed for 235 yards and two touchdowns against New York.

Also, the 49ers fear that rookie defensive end Mykel Williams tore the ACL in his right knee in the fourth quarter while pressuring Giants quarterback Jaxson Dart. Williams, the 11th overall pick in the 2025 draft, will undergo further testing on Monday.

“He’s just down and you never know. Hopefully it’s not the worst but, if it is, hey, that sucks for this year,” Shanahan said. “But that’s all it sucks for. You’ll be back next year and this won’t affect you at all.”

–Field Level Media

September 28, 2025; Santa Clara, California, USA; San Francisco 49ers quarterback Brock Purdy (13) during the third quarter against the Jacksonville Jaguars at Levi's Stadium. Mandatory Credit: Kyle Terada-Imagn Images

49ers’ Brock Purdy (toe) questionable, but Mac Jones starting vs. Giants

San Francisco 49ers quarterback Brock Purdy is listed as questionable for Sunday’s game against the New York Giants but Mac Jones will once again draw the start.

San Francisco coach Kyle Shanahan made the announcement Friday afternoon that Jones will start while indicating Purdy (toe) has made progress.

“(Purdy) has a chance to be available,” Shanahan said.

Jones will be starting for the fifth straight game and seventh time overall. The 49ers (5-3) are 4-2 with him in the starting role.

Purdy was initially hurt during the season-opening 17-13 victory over against the Seattle Seahawks and missed the next two games. He aggravated the injury during a 26-21 home loss against the Jacksonville Jaguars in Week 4.

Purdy was listed as limited in practice Friday for the third straight day. However, Shanahan said that Purdy’s toe isn’t fully healthy.

“He didn’t get all the starter reps this week,” Shanahan said. “As soon as he had a chance to get through practice and stuff, the first time (ahead of Week 4), we let him get all those starter reps, and it was great. And then, there was a chance he could re-hurt it in the game, and he did, and he’s been out for the last month.

“He got more reps this week, but we weren’t going to commit to all of that, like we did last time. I think it’s easing him back more than last time.”

If it turns out Purdy isn’t available Sunday, Adrian Martinez will again serve as the No. 2 quarterback.

Jones has stood out for the 49ers by passing for 1,597 yards and eight touchdowns against five interceptions. Purdy has completed 48 of 73 passes for 586 yards, with four touchdowns and four interceptions in his two games as a starter.

San Francisco receiver Ricky Pearsall (knee) will miss his fifth straight game. Others who will sit out against the Giants are center Jake Brendel (hamstring) and defensive ends Yetur Gross-Matos (knee/hamstring) and Bryce Huff (hamstring).

In addition, five other 49ers join Purdy as questionable. They are guard Ben Bartch (ankle), offensive tackle Spencer Burford (knee), defensive tackles Jordan Elliott (ankle) and Sam Okuayinonu (ankle) and linebacker Dee Winters (knee).

–Field Level Media

Sep 28, 2025; Santa Clara, California, USA; San Francisco 49ers quarterback Brock Purdy (13) after the game against the Jacksonville Jaguars at Levi's Stadium. Mandatory Credit: Darren Yamashita-Imagn Images

Mac Jones to start vs. Texans, Brock Purdy out again

Mac Jones will again be the starting quarterback for the San Francisco 49ers after Brock Purdy was ruled out of Sunday’s game against the Houston Texans due to his toe injury.

It will mark the fourth straight game and sixth overall that Purdy has missed this season. He was injured in a Week 1 victory over the Seattle Seahawks and aggravated the toe during a Week 4 loss to the Jacksonville Jaguars.

San Francisco is 4-1 when Jones starts this season. He has passed for 1,404 yards, six touchdowns and four interceptions.

Receiver Ricky Pearsall (knee) will miss his fourth straight game. Also ruled out on Friday were center Jake Brendel (hamstring) and defensive ends Bryce Huff (hamstring) and Yetur Gross-Matos (knee/hamstring).

Cornerback Deommodore Lenoir (quadriceps), linebacker Luke Gifford (hamstring) and offensive lineman Spencer Burford (knee) are questionable.

–Field Level Media

Dec 17, 2023; Glendale, Arizona, USA; San Francisco 49ers quarterback Brock Purdy (13) with wide receiver Brandon Aiyuk (11) against the Arizona Cardinals at State Farm Stadium. Mandatory Credit: Mark J. Rebilas-USA TODAY Sports

John Lynch: 49ers’ Brock Purdy, Brandon Aiyuk getting closer

San Francisco 49ers quarterback Brock Purdy’s season to date has largely been derailed by a toe injury.

He sustained the injury in Week 1, returned in Week 4 but has missed the last three games after dealing with a setback in his recovery.

Real details about a possible timeline for return to action for Purdy, who returned to practice in a limited capacity Oct. 15 and remained limited at Wednesday’s practice, have been scarce.

In a radio interview Thursday with local station KNBR, 49ers GM John Lynch made it clear that Purdy is getting closer to a return.

“What I can tell everyone is that we’re being (incredibly diligent),” Lynch said. “We’ve gotten so many opinions on this thing, and it’s been pretty consistent. He’s doing a really good job. We’re taking the appropriate measures, and what I can tell you is he gets better each week, each day. I do think we’re getting closer to him returning.”

Still, no firm timetable has been established for Purdy’s return.

“A hard timeline (is difficult to set) because it’s kind of a feel thing,” Lynch added. “And how he feels, that’s still out there and TBD, but we’re getting closer, we do know that. I think this week, in particular, last week, I think we made some progress. And so, that has Brock encouraged. It has everyone encouraged.

“We’re trusting Brock, we’re trusting the doctors. We’ll make a good decision on it, and that’s why it’s taken some time.”

Lynch also provided an update on receiver Brandon Aiyuk, who hasn’t played this season after tearing his ACL and MCL last October. Like with Purdy, Lynch is optimistic about his potential to return as he is just past the one-year mark from when he sustained the injuries.

“Oh, yeah, there’s hope he plays,” Lynch said of Aiyuk. “There’s, more importantly than hope, there’s some evidence. He’s making really good progress. He’s been putting in the time, and I think that it’s coming nearer as to when he’s going to be out there.”

San Francisco has kept winning in spite of being without Purdy, Aiyuk and a host of other important players on both sides of the ball.

The 49ers (5-2) are in a three-way tie atop the NFC West with the Seattle Seahawks and Los Angeles Rams heading into Sunday’s road game with the Houston Texans (2-4).

–Field Level Media

Sep 28, 2025; Santa Clara, California, USA; San Francisco 49ers quarterback Brock Purdy (13) after the game against the Jacksonville Jaguars at Levi's Stadium. Mandatory Credit: Darren Yamashita-Imagn Images

49ers QB Brock Purdy out again, Mac Jones questionable vs. Bucs

San Francisco quarterback Brock Purdy will miss his second straight game and fourth in the past five due to his turf toe injury when the 49ers visit the Tampa Bay Buccaneers on Sunday.

Purdy was initially injured during the season-opening game against the Seattle Seahawks and aggravated it during a Week 4 loss to the Jacksonville Jaguars. San Francisco coach Kyle Shanahan said earlier this week that the team isn’t considering placing Purdy on injured reserve.

Complicating matters is that backup quarterback Mac Jones is dealing with knee and oblique injuries and is listed as questionable. Jones aggravated the left knee ailment and injured the oblique during a victory over the Los Angeles Rams on Oct. 2.

Jones completed 33 of 49 passes for 342 yards and two touchdowns against the Rams. He has passed for 905 yards, six touchdowns and one interception in 129 pass attempts.

The third-string quarterback for the 49ers is Adrian Martinez, who has never played in an NFL game. He was promoted to the active roster hours before the game against the Rams.

Four other players were ruled out for the 49ers: receivers Ricky Pearsall (knee) and Jordan Watkins (calf) and defensive linemen Kevin Gaines (pectoral) and Yetur Gross-Matos (knee/hamstring).

In addition to Jones, receiver Jauan Jennings (rib/ankle), defensive linemen Alfred Collins (knee) and Kalia Davis (hand) and cornerback Upton Stout (ankle) and safety Malik Mustapha (knee).

Defensive lineman Robert Beal (ankle) didn’t practice all week and is a candidate to be placed on injured reserve.

–Field Level Media

Sep 28, 2025; Santa Clara, California, USA; San Francisco 49ers quarterback Brock Purdy (13) passes the ball during the first half against the Jacksonville Jaguars at Levi's Stadium. Mandatory Credit: Kyle Terada-Imagn Images

49ers QB Brock Purdy (toe) misses practice, Mac Jones limited

San Francisco 49ers quarterback Brock Purdy missed practice Wednesday and backup Mac Jones was limited while dealing with two injuries.

Purdy missed three of the past four games with a turf toe issue and his availability for Sunday’s game at the Tampa Bay Buccaneers doesn’t look promising.

49ers coach Kyle Shanahan told reporters he doesn’t believe Purdy needs a stint on injured reserve.

“It hasn’t been a thought on (placing Purdy on) IR,” Shanahan said. “He’s progressing.”

Jones has been dealing with a left knee issue since Week 3. Shanahan said Jones also has an oblique injury, which apparently occurred while he was getting hit hard and often during a 26-23 overtime victory over the Los Angeles Rams on Oct. 2.

The third quarterback for the 49ers is Adrian Martinez, who was promoted from the practice squad last week.

There was a time against the Rams where Jones remained down on the ground from a hit and eventually was gingerly helped off the field. But he was back on the field when San Francisco next possessed the ball.

Purdy was one of seven 49ers slated to miss Wednesday’s practice due to injuries.

Prior to the workout, Shanahan said receivers Jauan Jennings (ankle/rib), Ricky Pearsall (knee) and Jordan Watkins (calf), defensive ends Robert Beal Jr. (ankle) and Yetur Gross-Matos (knee/hamstring) and defensive tackle Alfred Collins (knee) would sit out.

Jones was one of five limited practice participants, along with defensive linemen C.J. West (thumb), Kalia Davis (hand) and Kevin Givens (pectoral) and cornerback Upton Stout (ankle).

Jones was 33-of-49 passing for 342 yards and two touchdowns against the Rams. He has passed for 905 yards, six touchdowns and one interceptions in 129 pass attempts.

Purdy has thrown for 586 yards, four touchdowns and four interceptions on 73 passes.

Also, Shanahan said that star tight end George Kittle (hamstring) could return to practice next week. He was injured in Week 1.

–Field Level Media

Sep 28, 2025; Santa Clara, California, USA; San Francisco 49ers quarterback Brock Purdy (13) passes the ball during the first half against the Jacksonville Jaguars at Levi's Stadium. Mandatory Credit: Kyle Terada-Imagn Images

49ers QB Brock Purdy (toe) ruled out vs. Rams

San Francisco 49ers quarterback Brock Purdy will miss Thursday night’s showdown against the host Los Angeles Rams due to his turf toe injury.

Purdy missed practice Wednesday for the third straight day.

This will mark Purdy’s third absence in four games due to the injury. He was initially hurt during a Week 1 contest against the Seattle Seahawks and aggravated the injury during last week’s 26-21 home loss against the Jacksonville Jaguars.

Mac Jones will draw the start for the 49ers (3-1). He started in Weeks 2 and 3 when Purdy was sidelined. Jones injured a knee during Week 3 but is now healthy and was a full practice participant all week.

Receivers Jauan Jennings (ankle/rib), Ricky Pearsall (knee) and Jordan Watkins (calf) and defensive end Robert Beal Jr. (ankle) also were declared out after not practicing this week.

Defensive lineman CJ West (thumb) is questionable. He was a limited participant on Wednesday.

Purdy, 25, has completed 48 of 73 passes for 586 yards, with four touchdowns and four interceptions in his two games as a starter. Jones, 27, is 53-of-80 passing for 563 yards, with four scores and one pick while going 2-0 in his two starts.

San Francisco will be shorthanded in terms of receiving targets as star tight end George Kittle (hamstring) is on injured reserve and standout receiver Brandon Aiyuk (knee) is still recovering from a serious knee injury sustained nearly 12 months ago.

–Field Level Media

Sep 21, 2025; Santa Clara, California, USA; San Francisco 49ers quarterback Brock Purdy (13) leaves the field following the game against the Arizona Cardinals at Levi's Stadium. Mandatory Credit: Cary Edmondson-Imagn Images

49ers QB Brock Purdy (toe) returns to start vs. Jaguars

Quarterback Brock Purdy will return to the starting lineup Sunday when the San Francisco 49ers visit the Jacksonville Jaguars.

Purdy was a full practice participant on Friday after his injured toe improved dramatically throughout the week. He missed the previous two games due to the ailment.

“He looked good,” 49ers coach Kyle Shanahan told reporters while confirming Purdy would start. “He got to do a lot more than last week and each day he got a lot better.”

Purdy was upbeat about his chances on Thursday when he met with the media.

“I really like where I’m at with the progress with it healing up and feeling better and dropping back, throwing,” Purdy said then. “It’s no secret like it’s been two-and-a-half weeks or so. And just overall, my toe is healed up. It’s gotten better.”

Purdy was injured during the season-opening 17-13 road victory over the Seattle Seahawks. He passed for 277 yards, two touchdowns and two interceptions.

Purdy also is listed as having a left shoulder injury but that ailment didn’t come into play regarding his availability.

Purdy returns at a time in which Mac Jones is bothered by a left knee injury. He started the past two games and passed for 563 yards, four touchdowns and one interception.

Jones is listed as questionable against the Jaguars and said he is able to play.

“I feel good,” Jones said. “Just like any other week, you’re going through the week, getting ready for the game plans as a backup or a starter. So, I feel comfortable doing both. I’ll be ready to play.”

Defensive lineman CJ West (thumb) and wideout Jordan Watkins (calf) were the only two San Francisco players ruled out of the contest.

Receivers Jauan Jennings (ankle/shoulder) and Ricky Pearsall (knee) are questionable, as are guard Connor Colby (groin) and cornerback Renardo Green (neck).

–Field Level Media

Sep 14, 2025; New Orleans, Louisiana, USA;  San Francisco 49ers quarterback Mac Jones (10) passes against the New Orleans Saints during the second half at Caesars Superdome. Mandatory Credit: Stephen Lew-Imagn Images

49ers expect to start Mac Jones again with Brock Purdy questionable

Mac Jones is in line to make a second straight start under center for the San Francisco 49ers after the team listed quarterback Brock Purdy as questionable for Sunday’s game against the Arizona Cardinals.

Purdy came away from the season-opening win against Seattle with toe and left shoulder injuries, his toe being the bigger concern. He sat out Week 2 while Jones guided the Niners to a 26-21 victory at New Orleans.

Coach Kyle Shanahan told reporters Friday afternoon that Purdy has made progress, though not enough to return to the starting role just yet.

“I think it’s highly unlikely that (Purdy) will start,” Shanahan said. “We’re just trying to see where he’s at to see if he can be a 2 or an emergency 3.”

Purdy was a limited participant in practice from Wednesday through Friday. He told reporters Thursday that he wants to play every game but is “trying to be smart with (his) body.”

The 49ers will need to know by Saturday whether Purdy will be active as the No. 2 quarterback or be kept inactive as the emergency third quarterback. That’s because they would need to promote practice squad quarterback Adrian Martinez to the active roster the day before the game in order to dub Purdy the emergency QB.

Jones, in his first season as San Francisco’s backup after three bumpy years in New England and one season in Jacksonville, completed 26 of 39 passes for 279 yards, three touchdowns and no interceptions against the Saints.

The 49ers also listed receiver Jauan Jennings (ankle, shoulder) and guard Connor Colby (groin) as questionable. Receiver Jordan Watkins (calf) and guard Spencer Burford (knee) were ruled out.

–Field Level Media